Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation.

Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation.

<h4>Background</h4>Chronic oral quercetin reduces blood pressure and restores endothelial dysfunction in hypertensive animals. However, quercetin (aglycone) is usually not present in plasma, because it is rapidly metabolized into conjugated, mostly inactive, metabolites. The aim of the s...

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Autores principales: Pilar Galindo, Isabel Rodriguez-Gómez, Susana González-Manzano, Montserrat Dueñas, Rosario Jiménez, Carmen Menéndez, Félix Vargas, Juan Tamargo, Celestino Santos-Buelga, Francisco Pérez-Vizcaíno, Juan Duarte
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/3e9aad156f1d4ea09eb2e72e99a16723
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