The compound TB47 is highly bactericidal against Mycobacterium ulcerans in a Buruli ulcer mouse model

The compound TB47 is highly bactericidal against Mycobacterium ulcerans in a Buruli ulcer mouse model

Combination therapy for Buruli ulcer (BU) is suboptimal. Here, Liu et al. show that the candidate drug TB47 has potent bactericidal activity against Mycobacterium ulcerans in vitro and in a mouse model, which underscores its potential for shortening the course of BU and treating other mycobacterial...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Yang Liu, Yamin Gao, Jianxiong Liu, Yaoju Tan, Zhiyong Liu, Chiranjibi Chhotaray, Huofeng Jiang, Zhili Lu, Gift Chiwala, Shuai Wang, Gaelle Makafe, Md Mahmudul Islam, H. M. Adnan Hameed, Xingshan Cai, Changwei Wang, Xinjie Li, Shouyong Tan, Tianyu Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/3eb099eeaf12439699ea5255f9ccaab6
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Combination therapy for Buruli ulcer (BU) is suboptimal. Here, Liu et al. show that the candidate drug TB47 has potent bactericidal activity against Mycobacterium ulcerans in vitro and in a mouse model, which underscores its potential for shortening the course of BU and treating other mycobacterial diseases.

Ejemplares similares