CROP: a CRISPR/Cas9 guide selection program based on mapping guide variants

CROP: a CRISPR/Cas9 guide selection program based on mapping guide variants

Abstract The off-target effect, in which DNA cleavage was conducted outside the targeted region, is a major problem which limits the applications of CRISPR/Cas9 genome editing system. CRISPR Off-target Predictor (CROP) is standalone program developed to address this problem by predicting off-target...

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Autores principales: Victor Aprilyanto, Redi Aditama, Zulfikar Achmad Tanjung, Condro Utomo, Tony Liwang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/3eb2522a7bed476db29ca112e577cb88
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