Asynchronous suppression of visual cortex during absence seizures in stargazer mice

Absence epilepsy is associated with frequent generalized spike-wave seizures and loss of awareness. Here the authors use 2-photon calcium imaging of primary visual cortex in a genetic mouse model of absence epilepsy and find that cortical neurons are less active and more loosely coupled to the seizu...

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Autores principales:	Jochen Meyer, Atul Maheshwari, Jeffrey Noebels, Stelios Smirnakis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3ebcd068ba1946c5b3c29784c6bf764e
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spelling	oai:doaj.org-article:3ebcd068ba1946c5b3c29784c6bf764e2021-12-02T16:49:55ZAsynchronous suppression of visual cortex during absence seizures in stargazer mice10.1038/s41467-018-04349-82041-1723https://doaj.org/article/3ebcd068ba1946c5b3c29784c6bf764e2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04349-8https://doaj.org/toc/2041-1723Absence epilepsy is associated with frequent generalized spike-wave seizures and loss of awareness. Here the authors use 2-photon calcium imaging of primary visual cortex in a genetic mouse model of absence epilepsy and find that cortical neurons are less active and more loosely coupled to the seizure EEG signature than previously believed.Jochen MeyerAtul MaheshwariJeffrey NoebelsStelios SmirnakisNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jochen Meyer Atul Maheshwari Jeffrey Noebels Stelios Smirnakis Asynchronous suppression of visual cortex during absence seizures in stargazer mice
description	Absence epilepsy is associated with frequent generalized spike-wave seizures and loss of awareness. Here the authors use 2-photon calcium imaging of primary visual cortex in a genetic mouse model of absence epilepsy and find that cortical neurons are less active and more loosely coupled to the seizure EEG signature than previously believed.
format	article
author	Jochen Meyer Atul Maheshwari Jeffrey Noebels Stelios Smirnakis
author_facet	Jochen Meyer Atul Maheshwari Jeffrey Noebels Stelios Smirnakis
author_sort	Jochen Meyer
title	Asynchronous suppression of visual cortex during absence seizures in stargazer mice
title_short	Asynchronous suppression of visual cortex during absence seizures in stargazer mice
title_full	Asynchronous suppression of visual cortex during absence seizures in stargazer mice
title_fullStr	Asynchronous suppression of visual cortex during absence seizures in stargazer mice
title_full_unstemmed	Asynchronous suppression of visual cortex during absence seizures in stargazer mice
title_sort	asynchronous suppression of visual cortex during absence seizures in stargazer mice
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/3ebcd068ba1946c5b3c29784c6bf764e
work_keys_str_mv	AT jochenmeyer asynchronoussuppressionofvisualcortexduringabsenceseizuresinstargazermice AT atulmaheshwari asynchronoussuppressionofvisualcortexduringabsenceseizuresinstargazermice AT jeffreynoebels asynchronoussuppressionofvisualcortexduringabsenceseizuresinstargazermice AT steliossmirnakis asynchronoussuppressionofvisualcortexduringabsenceseizuresinstargazermice
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Asynchronous suppression of visual cortex during absence seizures in stargazer mice

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