The features of the process of lipid peroxidation and antioxidant protection in women of reproductive age diagnosed with polycystic ovary syndrome (literature review)

The article presents the review of scientific sources devoted to the functional state of lipid peroxidation and antioxidant protection (LPO-AOD), which provides redox homeostasis and determines the body's resistance to adverse influences. The main functions of the LPO are the regulation of rene...

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Autor principal:	O. V. Panarina
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2018
Materias:	polycystic ovary syndrome lipid peroxidation antioxidant protection hormones hyperandrogenia Science Q
Acceso en línea:	https://doaj.org/article/3ebf4a92d20d436cb74ffbd770e00b56
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spelling	oai:doaj.org-article:3ebf4a92d20d436cb74ffbd770e00b562021-11-23T06:14:40ZThe features of the process of lipid peroxidation and antioxidant protection in women of reproductive age diagnosed with polycystic ovary syndrome (literature review)2541-94202587-959610.29413/ABS.2018-3.3.13https://doaj.org/article/3ebf4a92d20d436cb74ffbd770e00b562018-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/589https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The article presents the review of scientific sources devoted to the functional state of lipid peroxidation and antioxidant protection (LPO-AOD), which provides redox homeostasis and determines the body's resistance to adverse influences. The main functions of the LPO are the regulation of renewal, decay of unsaturated structural lipids, lipid permeability of biological membranes. A constantly flowing physiological process has a chain free radical mechanism, the substrates of which are polyunsaturated fatty acids and the main lipids of the blood plasma - cholesterol and triglycerides. Disturbance of the POL-AOD balance leads to oxidative stress, which is an importantfactor in the disruption of cell function and, therefore, the emergence of pathological processes. For many years, researchers around the world have been paying close attention to the study of the etiology and pathogenesis of diseases such as polycystic ovary syndrome (PCOS), the causes of which are diverse. This common form of endocrine pathology affects up to 20 % of women of reproductive age and is directly related to metabolic disorders (dyslipidemia, hyperinsulinism, insulin resistance, glucose tolerance). This leads to the development of hypertension, abdominal-visceral obesity, early atherosclerosis and coronary heart disease. Serious consequences can also be metabolic dysfunction, ovulatory infertility, premature birth, perinatal mortality, cancer, etc. Currently there are several studies showing the relationship of processes of LPO-AOD and neuroendocrine regulation. However, there is no comprehensive assessment of the functional relationship between sex hormones and the system of LPO-AOD in women with PCOS, which causes even greater interest for the study.O. V. PanarinaScientific Сentre for Family Health and Human Reproduction Problemsarticlepolycystic ovary syndromelipid peroxidationantioxidant protection hormoneshyperandrogeniaScienceQRUActa Biomedica Scientifica, Vol 3, Iss 3, Pp 88-92 (2018)
institution	DOAJ
collection	DOAJ
language	RU
topic	polycystic ovary syndrome lipid peroxidation antioxidant protection hormones hyperandrogenia Science Q
spellingShingle	polycystic ovary syndrome lipid peroxidation antioxidant protection hormones hyperandrogenia Science Q O. V. Panarina The features of the process of lipid peroxidation and antioxidant protection in women of reproductive age diagnosed with polycystic ovary syndrome (literature review)
description	The article presents the review of scientific sources devoted to the functional state of lipid peroxidation and antioxidant protection (LPO-AOD), which provides redox homeostasis and determines the body's resistance to adverse influences. The main functions of the LPO are the regulation of renewal, decay of unsaturated structural lipids, lipid permeability of biological membranes. A constantly flowing physiological process has a chain free radical mechanism, the substrates of which are polyunsaturated fatty acids and the main lipids of the blood plasma - cholesterol and triglycerides. Disturbance of the POL-AOD balance leads to oxidative stress, which is an importantfactor in the disruption of cell function and, therefore, the emergence of pathological processes. For many years, researchers around the world have been paying close attention to the study of the etiology and pathogenesis of diseases such as polycystic ovary syndrome (PCOS), the causes of which are diverse. This common form of endocrine pathology affects up to 20 % of women of reproductive age and is directly related to metabolic disorders (dyslipidemia, hyperinsulinism, insulin resistance, glucose tolerance). This leads to the development of hypertension, abdominal-visceral obesity, early atherosclerosis and coronary heart disease. Serious consequences can also be metabolic dysfunction, ovulatory infertility, premature birth, perinatal mortality, cancer, etc. Currently there are several studies showing the relationship of processes of LPO-AOD and neuroendocrine regulation. However, there is no comprehensive assessment of the functional relationship between sex hormones and the system of LPO-AOD in women with PCOS, which causes even greater interest for the study.
format	article
author	O. V. Panarina
author_facet	O. V. Panarina
author_sort	O. V. Panarina
title	The features of the process of lipid peroxidation and antioxidant protection in women of reproductive age diagnosed with polycystic ovary syndrome (literature review)
title_short	The features of the process of lipid peroxidation and antioxidant protection in women of reproductive age diagnosed with polycystic ovary syndrome (literature review)
title_full	The features of the process of lipid peroxidation and antioxidant protection in women of reproductive age diagnosed with polycystic ovary syndrome (literature review)
title_fullStr	The features of the process of lipid peroxidation and antioxidant protection in women of reproductive age diagnosed with polycystic ovary syndrome (literature review)
title_full_unstemmed	The features of the process of lipid peroxidation and antioxidant protection in women of reproductive age diagnosed with polycystic ovary syndrome (literature review)
title_sort	features of the process of lipid peroxidation and antioxidant protection in women of reproductive age diagnosed with polycystic ovary syndrome (literature review)
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2018
url	https://doaj.org/article/3ebf4a92d20d436cb74ffbd770e00b56
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The features of the process of lipid peroxidation and antioxidant protection in women of reproductive age diagnosed with polycystic ovary syndrome (literature review)

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