Isotope separation of 176Lu a precursor to 177Lu medical isotope using broadband lasers

Abstract A new photoionization scheme accessible by Rhodamine dye lasers is proposed for the isotope separation of 176Lu. $$5d6s^{2}\,{^{2}D_{{3/2}}} (0.0\, {\text{cm}}^{{ - 1}} )\mathop{\longrightarrow}\limits^{{573.8130\, {\text{nm}}}}5d6s6p\,{^{4}F_{{3/2}}^{o}} \left( {17427.28\, {\text{cm}}^{{ -...

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Autor principal:	M. V. Suryanarayana
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/3ec23cff77d24410b2728e3ac776c3c8
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spelling	oai:doaj.org-article:3ec23cff77d24410b2728e3ac776c3c82021-12-02T16:30:46ZIsotope separation of 176Lu a precursor to 177Lu medical isotope using broadband lasers10.1038/s41598-021-85414-z2045-2322https://doaj.org/article/3ec23cff77d24410b2728e3ac776c3c82021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-85414-zhttps://doaj.org/toc/2045-2322Abstract A new photoionization scheme accessible by Rhodamine dye lasers is proposed for the isotope separation of 176Lu. $$5d6s^{2}\,{^{2}D_{{3/2}}} (0.0\, {\text{cm}}^{{ - 1}} )\mathop{\longrightarrow}\limits^{{573.8130\, {\text{nm}}}}5d6s6p\,{^{4}F_{{3/2}}^{o}} \left( {17427.28\, {\text{cm}}^{{ - 1}} } \right)\mathop{\longrightarrow}\limits^{{560.3114\, {\text{nm}}}}$$ 5 d 6 s 2 2 D 3 / 2 ( 0.0 cm - 1 ) ⟶ 573.8130 nm 5 d 6 s 6 p 4 F 3 / 2 o 17427.28 cm - 1 ⟶ 560.3114 nm $$6s{6p}^{2}\,{^{4}{P}_{5/2}}\left(35274.5 \,{\text{cm}}^{-1}\right){\to } Autoionization\, State {\to }{Lu}^{+}$$ 6 s 6 p 2 4 P 5 / 2 35274.5 cm - 1 → A u t o i o n i z a t i o n S t a t e → Lu + Optimum conditions for the laser isotope separation have been theoretically computed and compared with the previously reported work. The enrichment of ~ 63% can be obtained with > 22 mg/h production rate even when broadband lasers with bandwidth of 500 MHz are employed for the two step excitation. The simplified system requirements for the photoionization scheme combined with a high production rate of 176Lu than previously reported is expected to reduce the global shortage of 176Lu isotope for medical applications.M. V. SuryanarayanaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q M. V. Suryanarayana Isotope separation of 176Lu a precursor to 177Lu medical isotope using broadband lasers
description	Abstract A new photoionization scheme accessible by Rhodamine dye lasers is proposed for the isotope separation of 176Lu. $$5d6s^{2}\,{^{2}D_{{3/2}}} (0.0\, {\text{cm}}^{{ - 1}} )\mathop{\longrightarrow}\limits^{{573.8130\, {\text{nm}}}}5d6s6p\,{^{4}F_{{3/2}}^{o}} \left( {17427.28\, {\text{cm}}^{{ - 1}} } \right)\mathop{\longrightarrow}\limits^{{560.3114\, {\text{nm}}}}$$ 5 d 6 s 2 2 D 3 / 2 ( 0.0 cm - 1 ) ⟶ 573.8130 nm 5 d 6 s 6 p 4 F 3 / 2 o 17427.28 cm - 1 ⟶ 560.3114 nm $$6s{6p}^{2}\,{^{4}{P}_{5/2}}\left(35274.5 \,{\text{cm}}^{-1}\right){\to } Autoionization\, State {\to }{Lu}^{+}$$ 6 s 6 p 2 4 P 5 / 2 35274.5 cm - 1 → A u t o i o n i z a t i o n S t a t e → Lu + Optimum conditions for the laser isotope separation have been theoretically computed and compared with the previously reported work. The enrichment of ~ 63% can be obtained with > 22 mg/h production rate even when broadband lasers with bandwidth of 500 MHz are employed for the two step excitation. The simplified system requirements for the photoionization scheme combined with a high production rate of 176Lu than previously reported is expected to reduce the global shortage of 176Lu isotope for medical applications.
format	article
author	M. V. Suryanarayana
author_facet	M. V. Suryanarayana
author_sort	M. V. Suryanarayana
title	Isotope separation of 176Lu a precursor to 177Lu medical isotope using broadband lasers
title_short	Isotope separation of 176Lu a precursor to 177Lu medical isotope using broadband lasers
title_full	Isotope separation of 176Lu a precursor to 177Lu medical isotope using broadband lasers
title_fullStr	Isotope separation of 176Lu a precursor to 177Lu medical isotope using broadband lasers
title_full_unstemmed	Isotope separation of 176Lu a precursor to 177Lu medical isotope using broadband lasers
title_sort	isotope separation of 176lu a precursor to 177lu medical isotope using broadband lasers
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/3ec23cff77d24410b2728e3ac776c3c8
work_keys_str_mv	AT mvsuryanarayana isotopeseparationof176luaprecursorto177lumedicalisotopeusingbroadbandlasers
_version_	1718383865725190144

Isotope separation of 176Lu a precursor to 177Lu medical isotope using broadband lasers

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