Recent Advances in Detection, Isolation, and Imaging Techniques for Sulfane Sulfur-Containing Biomolecules

Hydrogen sulfide and its oxidation products are involved in many biological processes, and sulfane sulfur compounds, which contain sulfur atoms bonded to other sulfur atom(s), as found in hydropersulfides (R-S-SH), polysulfides (R-S-S<sub>n</sub>-S-R), hydrogen polysulfides (H<sub>...

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Autores principales:	Honami Echizen, Eita Sasaki, Kenjiro Hanaoka
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	sulfane sulfur hydrogen sulfide hydrogen persulfide polysulfide fluorescent probes Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/3ec27413ecf8496181cd141acd901516
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spelling	oai:doaj.org-article:3ec27413ecf8496181cd141acd9015162021-11-25T16:51:45ZRecent Advances in Detection, Isolation, and Imaging Techniques for Sulfane Sulfur-Containing Biomolecules10.3390/biom111115532218-273Xhttps://doaj.org/article/3ec27413ecf8496181cd141acd9015162021-10-01T00:00:00Zhttps://www.mdpi.com/2218-273X/11/11/1553https://doaj.org/toc/2218-273XHydrogen sulfide and its oxidation products are involved in many biological processes, and sulfane sulfur compounds, which contain sulfur atoms bonded to other sulfur atom(s), as found in hydropersulfides (R-S-SH), polysulfides (R-S-S<sub>n</sub>-S-R), hydrogen polysulfides (H<sub>2</sub>S<sub>n</sub>), etc., have attracted increasing interest. To characterize their physiological and pathophysiological roles, selective detection techniques are required. Classically, sulfane sulfur compounds can be detected by cyanolysis, involving nucleophilic attack by cyanide ion to cleave the sulfur–sulfur bonds. The generated thiocyanate reacts with ferric ion, and the resulting ferric thiocyanate complex can be easily detected by absorption spectroscopy. Recent exploration of the properties of sulfane sulfur compounds as both nucleophiles and electrophiles has led to the development of various chemical techniques for detection, isolation, and bioimaging of sulfane sulfur compounds in biological samples. These include tag-switch techniques, LC-MS/MS, Raman spectroscopy, and fluorescent probes. Herein, we present an overview of the techniques available for specific detection of sulfane sulfur species in biological contexts.Honami EchizenEita SasakiKenjiro HanaokaMDPI AGarticlesulfane sulfurhydrogen sulfidehydrogen persulfidepolysulfidefluorescent probesMicrobiologyQR1-502ENBiomolecules, Vol 11, Iss 1553, p 1553 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	sulfane sulfur hydrogen sulfide hydrogen persulfide polysulfide fluorescent probes Microbiology QR1-502
spellingShingle	sulfane sulfur hydrogen sulfide hydrogen persulfide polysulfide fluorescent probes Microbiology QR1-502 Honami Echizen Eita Sasaki Kenjiro Hanaoka Recent Advances in Detection, Isolation, and Imaging Techniques for Sulfane Sulfur-Containing Biomolecules
description	Hydrogen sulfide and its oxidation products are involved in many biological processes, and sulfane sulfur compounds, which contain sulfur atoms bonded to other sulfur atom(s), as found in hydropersulfides (R-S-SH), polysulfides (R-S-S<sub>n</sub>-S-R), hydrogen polysulfides (H<sub>2</sub>S<sub>n</sub>), etc., have attracted increasing interest. To characterize their physiological and pathophysiological roles, selective detection techniques are required. Classically, sulfane sulfur compounds can be detected by cyanolysis, involving nucleophilic attack by cyanide ion to cleave the sulfur–sulfur bonds. The generated thiocyanate reacts with ferric ion, and the resulting ferric thiocyanate complex can be easily detected by absorption spectroscopy. Recent exploration of the properties of sulfane sulfur compounds as both nucleophiles and electrophiles has led to the development of various chemical techniques for detection, isolation, and bioimaging of sulfane sulfur compounds in biological samples. These include tag-switch techniques, LC-MS/MS, Raman spectroscopy, and fluorescent probes. Herein, we present an overview of the techniques available for specific detection of sulfane sulfur species in biological contexts.
format	article
author	Honami Echizen Eita Sasaki Kenjiro Hanaoka
author_facet	Honami Echizen Eita Sasaki Kenjiro Hanaoka
author_sort	Honami Echizen
title	Recent Advances in Detection, Isolation, and Imaging Techniques for Sulfane Sulfur-Containing Biomolecules
title_short	Recent Advances in Detection, Isolation, and Imaging Techniques for Sulfane Sulfur-Containing Biomolecules
title_full	Recent Advances in Detection, Isolation, and Imaging Techniques for Sulfane Sulfur-Containing Biomolecules
title_fullStr	Recent Advances in Detection, Isolation, and Imaging Techniques for Sulfane Sulfur-Containing Biomolecules
title_full_unstemmed	Recent Advances in Detection, Isolation, and Imaging Techniques for Sulfane Sulfur-Containing Biomolecules
title_sort	recent advances in detection, isolation, and imaging techniques for sulfane sulfur-containing biomolecules
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/3ec27413ecf8496181cd141acd901516
work_keys_str_mv	AT honamiechizen recentadvancesindetectionisolationandimagingtechniquesforsulfanesulfurcontainingbiomolecules AT eitasasaki recentadvancesindetectionisolationandimagingtechniquesforsulfanesulfurcontainingbiomolecules AT kenjirohanaoka recentadvancesindetectionisolationandimagingtechniquesforsulfanesulfurcontainingbiomolecules
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Recent Advances in Detection, Isolation, and Imaging Techniques for Sulfane Sulfur-Containing Biomolecules

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