Post-capillary venules are the key locus for transcytosis-mediated brain delivery of therapeutic nanoparticles
Limited understanding of the interactions between nanoparticle drug carriers and the blood-brain barrier underlies many translational failures in treatments of brain disorders. Here the authors use two-photon microscopy in mice to characterize the receptor-mediated transcytosis of nanoparticles at a...
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Autores principales: | Krzysztof Kucharz, Kasper Kristensen, Kasper Bendix Johnsen, Mette Aagaard Lund, Micael Lønstrup, Torben Moos, Thomas Lars Andresen, Martin Johannes Lauritzen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/3ecb3577f7e2486e85315477978e25ca |
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