Sexual-dimorphism in human immune system aging

Whether the immune system aging differs between men and women is barely known. Here the authors characterize gene expression, chromatin state and immune subset composition in the blood of healthy humans 22 to 93 years of age, uncovering shared as well as sex-unique alterations, and create a web reso...

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Autores principales:	Eladio J. Márquez, Cheng-han Chung, Radu Marches, Robert J. Rossi, Djamel Nehar-Belaid, Alper Eroglu, David J. Mellert, George A. Kuchel, Jacques Banchereau, Duygu Ucar
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3eccfba4f71b4c47b6e7ca50b74ee79d
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spelling	oai:doaj.org-article:3eccfba4f71b4c47b6e7ca50b74ee79d2021-12-02T14:40:28ZSexual-dimorphism in human immune system aging10.1038/s41467-020-14396-92041-1723https://doaj.org/article/3eccfba4f71b4c47b6e7ca50b74ee79d2020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14396-9https://doaj.org/toc/2041-1723Whether the immune system aging differs between men and women is barely known. Here the authors characterize gene expression, chromatin state and immune subset composition in the blood of healthy humans 22 to 93 years of age, uncovering shared as well as sex-unique alterations, and create a web resource to interactively explore the data.Eladio J. MárquezCheng-han ChungRadu MarchesRobert J. RossiDjamel Nehar-BelaidAlper ErogluDavid J. MellertGeorge A. KuchelJacques BanchereauDuygu UcarNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Eladio J. Márquez Cheng-han Chung Radu Marches Robert J. Rossi Djamel Nehar-Belaid Alper Eroglu David J. Mellert George A. Kuchel Jacques Banchereau Duygu Ucar Sexual-dimorphism in human immune system aging
description	Whether the immune system aging differs between men and women is barely known. Here the authors characterize gene expression, chromatin state and immune subset composition in the blood of healthy humans 22 to 93 years of age, uncovering shared as well as sex-unique alterations, and create a web resource to interactively explore the data.
format	article
author	Eladio J. Márquez Cheng-han Chung Radu Marches Robert J. Rossi Djamel Nehar-Belaid Alper Eroglu David J. Mellert George A. Kuchel Jacques Banchereau Duygu Ucar
author_facet	Eladio J. Márquez Cheng-han Chung Radu Marches Robert J. Rossi Djamel Nehar-Belaid Alper Eroglu David J. Mellert George A. Kuchel Jacques Banchereau Duygu Ucar
author_sort	Eladio J. Márquez
title	Sexual-dimorphism in human immune system aging
title_short	Sexual-dimorphism in human immune system aging
title_full	Sexual-dimorphism in human immune system aging
title_fullStr	Sexual-dimorphism in human immune system aging
title_full_unstemmed	Sexual-dimorphism in human immune system aging
title_sort	sexual-dimorphism in human immune system aging
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/3eccfba4f71b4c47b6e7ca50b74ee79d
work_keys_str_mv	AT eladiojmarquez sexualdimorphisminhumanimmunesystemaging AT chenghanchung sexualdimorphisminhumanimmunesystemaging AT radumarches sexualdimorphisminhumanimmunesystemaging AT robertjrossi sexualdimorphisminhumanimmunesystemaging AT djamelneharbelaid sexualdimorphisminhumanimmunesystemaging AT alpereroglu sexualdimorphisminhumanimmunesystemaging AT davidjmellert sexualdimorphisminhumanimmunesystemaging AT georgeakuchel sexualdimorphisminhumanimmunesystemaging AT jacquesbanchereau sexualdimorphisminhumanimmunesystemaging AT duyguucar sexualdimorphisminhumanimmunesystemaging
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Sexual-dimorphism in human immune system aging

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