Sexual-dimorphism in human immune system aging
Whether the immune system aging differs between men and women is barely known. Here the authors characterize gene expression, chromatin state and immune subset composition in the blood of healthy humans 22 to 93 years of age, uncovering shared as well as sex-unique alterations, and create a web reso...
Saved in:
Main Authors: | , , , , , , , , , |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
|
Subjects: | |
Online Access: | https://doaj.org/article/3eccfba4f71b4c47b6e7ca50b74ee79d |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:doaj.org-article:3eccfba4f71b4c47b6e7ca50b74ee79d |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:3eccfba4f71b4c47b6e7ca50b74ee79d2021-12-02T14:40:28ZSexual-dimorphism in human immune system aging10.1038/s41467-020-14396-92041-1723https://doaj.org/article/3eccfba4f71b4c47b6e7ca50b74ee79d2020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14396-9https://doaj.org/toc/2041-1723Whether the immune system aging differs between men and women is barely known. Here the authors characterize gene expression, chromatin state and immune subset composition in the blood of healthy humans 22 to 93 years of age, uncovering shared as well as sex-unique alterations, and create a web resource to interactively explore the data.Eladio J. MárquezCheng-han ChungRadu MarchesRobert J. RossiDjamel Nehar-BelaidAlper ErogluDavid J. MellertGeorge A. KuchelJacques BanchereauDuygu UcarNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Eladio J. Márquez Cheng-han Chung Radu Marches Robert J. Rossi Djamel Nehar-Belaid Alper Eroglu David J. Mellert George A. Kuchel Jacques Banchereau Duygu Ucar Sexual-dimorphism in human immune system aging |
description |
Whether the immune system aging differs between men and women is barely known. Here the authors characterize gene expression, chromatin state and immune subset composition in the blood of healthy humans 22 to 93 years of age, uncovering shared as well as sex-unique alterations, and create a web resource to interactively explore the data. |
format |
article |
author |
Eladio J. Márquez Cheng-han Chung Radu Marches Robert J. Rossi Djamel Nehar-Belaid Alper Eroglu David J. Mellert George A. Kuchel Jacques Banchereau Duygu Ucar |
author_facet |
Eladio J. Márquez Cheng-han Chung Radu Marches Robert J. Rossi Djamel Nehar-Belaid Alper Eroglu David J. Mellert George A. Kuchel Jacques Banchereau Duygu Ucar |
author_sort |
Eladio J. Márquez |
title |
Sexual-dimorphism in human immune system aging |
title_short |
Sexual-dimorphism in human immune system aging |
title_full |
Sexual-dimorphism in human immune system aging |
title_fullStr |
Sexual-dimorphism in human immune system aging |
title_full_unstemmed |
Sexual-dimorphism in human immune system aging |
title_sort |
sexual-dimorphism in human immune system aging |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/3eccfba4f71b4c47b6e7ca50b74ee79d |
work_keys_str_mv |
AT eladiojmarquez sexualdimorphisminhumanimmunesystemaging AT chenghanchung sexualdimorphisminhumanimmunesystemaging AT radumarches sexualdimorphisminhumanimmunesystemaging AT robertjrossi sexualdimorphisminhumanimmunesystemaging AT djamelneharbelaid sexualdimorphisminhumanimmunesystemaging AT alpereroglu sexualdimorphisminhumanimmunesystemaging AT davidjmellert sexualdimorphisminhumanimmunesystemaging AT georgeakuchel sexualdimorphisminhumanimmunesystemaging AT jacquesbanchereau sexualdimorphisminhumanimmunesystemaging AT duyguucar sexualdimorphisminhumanimmunesystemaging |
_version_ |
1718390290154258432 |