Genetic and functional analysis of the DLG4 gene encoding the post-synaptic density protein 95 in schizophrenia.

Hypofunction of N-methyl-D-aspartate (NMDA) receptor-mediated signal transduction has been implicated in the pathophysiology of schizophrenia. Post-synaptic density protein 95 (PSD95) plays a critical role in regulating the trafficking and activity of the NMDA receptor and altered expression of the...

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Autores principales: Min-Chih Cheng, Chao-Lin Lu, Sy-Ueng Luu, Ho-Min Tsai, Shih-Hsin Hsu, Tzu-Ting Chen, Chia-Hsiang Chen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/3ece60630b394a5bac0f92eb316f1499
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