The Protein Kinase A-Dependent Phosphoproteome of the Human Pathogen <named-content content-type="genus-species">Aspergillus fumigatus</named-content> Reveals Diverse Virulence-Associated Kinase Targets

The Protein Kinase A-Dependent Phosphoproteome of the Human Pathogen <named-content content-type="genus-species">Aspergillus fumigatus</named-content> Reveals Diverse Virulence-Associated Kinase Targets

ABSTRACT Protein kinase A (PKA) signaling plays a critical role in the growth and development of all eukaryotic microbes. However, few direct targets have been characterized in any organism. The fungus Aspergillus fumigatus is a leading infectious cause of death in immunocompromised patients, but th...

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Autores principales: E. Keats Shwab, Praveen R. Juvvadi, Greg Waitt, Shareef Shaheen, John Allen, Erik J. Soderblom, Benjamin G. Bobay, Yohannes G. Asfaw, M. Arthur Moseley, William J. Steinbach
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
Aspergillus
filamentous fungi
fungal pathogen
protein kinase A
protein phosphorylation
proteomics
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/3ece9604418c42c0a8b4f8936774ea35
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