Spreading depression as an innate antiseizure mechanism

Spreading depression is a prolonged depolarization in the CNS associated with several neurological diseases. Here the authors demonstrate a reciprocal relationship between spreading depression and seizures in an animal model.

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Autores principales: Isra Tamim, David Y. Chung, Andreia Lopes de Morais, Inge C. M. Loonen, Tao Qin, Amrit Misra, Frieder Schlunk, Matthias Endres, Steven J. Schiff, Cenk Ayata
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3ed28318479d4356a4b92cb55f229bad
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spelling oai:doaj.org-article:3ed28318479d4356a4b92cb55f229bad2021-12-02T18:02:47ZSpreading depression as an innate antiseizure mechanism10.1038/s41467-021-22464-x2041-1723https://doaj.org/article/3ed28318479d4356a4b92cb55f229bad2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22464-xhttps://doaj.org/toc/2041-1723Spreading depression is a prolonged depolarization in the CNS associated with several neurological diseases. Here the authors demonstrate a reciprocal relationship between spreading depression and seizures in an animal model.Isra TamimDavid Y. ChungAndreia Lopes de MoraisInge C. M. LoonenTao QinAmrit MisraFrieder SchlunkMatthias EndresSteven J. SchiffCenk AyataNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Isra Tamim
David Y. Chung
Andreia Lopes de Morais
Inge C. M. Loonen
Tao Qin
Amrit Misra
Frieder Schlunk
Matthias Endres
Steven J. Schiff
Cenk Ayata
Spreading depression as an innate antiseizure mechanism
description Spreading depression is a prolonged depolarization in the CNS associated with several neurological diseases. Here the authors demonstrate a reciprocal relationship between spreading depression and seizures in an animal model.
format article
author Isra Tamim
David Y. Chung
Andreia Lopes de Morais
Inge C. M. Loonen
Tao Qin
Amrit Misra
Frieder Schlunk
Matthias Endres
Steven J. Schiff
Cenk Ayata
author_facet Isra Tamim
David Y. Chung
Andreia Lopes de Morais
Inge C. M. Loonen
Tao Qin
Amrit Misra
Frieder Schlunk
Matthias Endres
Steven J. Schiff
Cenk Ayata
author_sort Isra Tamim
title Spreading depression as an innate antiseizure mechanism
title_short Spreading depression as an innate antiseizure mechanism
title_full Spreading depression as an innate antiseizure mechanism
title_fullStr Spreading depression as an innate antiseizure mechanism
title_full_unstemmed Spreading depression as an innate antiseizure mechanism
title_sort spreading depression as an innate antiseizure mechanism
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/3ed28318479d4356a4b92cb55f229bad
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