Implementation and benchmarking of a novel analytical framework to clinically evaluate tumor-specific fluorescent tracers

Fluorescent tracers are being tested in clinical trials to improve detection of tumor margins, but procedures are not standardised. Here, the authors develop an analytical framework that is compatible with the workflow in the operating theatre, and show that it leads to an 88% increase in intraopera...

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Autores principales:	Marjory Koller, Si-Qi Qiu, Matthijs D. Linssen, Liesbeth Jansen, Wendy Kelder, Jakob de Vries, Inge Kruithof, Guo-Jun Zhang, Dominic J. Robinson, Wouter B. Nagengast, Annelies Jorritsma-Smit, Bert van der Vegt, Gooitzen M. van Dam
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3ed830983e42469387cbdb1c666bbe45
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spelling	oai:doaj.org-article:3ed830983e42469387cbdb1c666bbe452021-12-02T15:33:58ZImplementation and benchmarking of a novel analytical framework to clinically evaluate tumor-specific fluorescent tracers10.1038/s41467-018-05727-y2041-1723https://doaj.org/article/3ed830983e42469387cbdb1c666bbe452018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05727-yhttps://doaj.org/toc/2041-1723Fluorescent tracers are being tested in clinical trials to improve detection of tumor margins, but procedures are not standardised. Here, the authors develop an analytical framework that is compatible with the workflow in the operating theatre, and show that it leads to an 88% increase in intraoperative detection of tumor margins in patients with breast cancer.Marjory KollerSi-Qi QiuMatthijs D. LinssenLiesbeth JansenWendy KelderJakob de VriesInge KruithofGuo-Jun ZhangDominic J. RobinsonWouter B. NagengastAnnelies Jorritsma-SmitBert van der VegtGooitzen M. van DamNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marjory Koller Si-Qi Qiu Matthijs D. Linssen Liesbeth Jansen Wendy Kelder Jakob de Vries Inge Kruithof Guo-Jun Zhang Dominic J. Robinson Wouter B. Nagengast Annelies Jorritsma-Smit Bert van der Vegt Gooitzen M. van Dam Implementation and benchmarking of a novel analytical framework to clinically evaluate tumor-specific fluorescent tracers
description	Fluorescent tracers are being tested in clinical trials to improve detection of tumor margins, but procedures are not standardised. Here, the authors develop an analytical framework that is compatible with the workflow in the operating theatre, and show that it leads to an 88% increase in intraoperative detection of tumor margins in patients with breast cancer.
format	article
author	Marjory Koller Si-Qi Qiu Matthijs D. Linssen Liesbeth Jansen Wendy Kelder Jakob de Vries Inge Kruithof Guo-Jun Zhang Dominic J. Robinson Wouter B. Nagengast Annelies Jorritsma-Smit Bert van der Vegt Gooitzen M. van Dam
author_facet	Marjory Koller Si-Qi Qiu Matthijs D. Linssen Liesbeth Jansen Wendy Kelder Jakob de Vries Inge Kruithof Guo-Jun Zhang Dominic J. Robinson Wouter B. Nagengast Annelies Jorritsma-Smit Bert van der Vegt Gooitzen M. van Dam
author_sort	Marjory Koller
title	Implementation and benchmarking of a novel analytical framework to clinically evaluate tumor-specific fluorescent tracers
title_short	Implementation and benchmarking of a novel analytical framework to clinically evaluate tumor-specific fluorescent tracers
title_full	Implementation and benchmarking of a novel analytical framework to clinically evaluate tumor-specific fluorescent tracers
title_fullStr	Implementation and benchmarking of a novel analytical framework to clinically evaluate tumor-specific fluorescent tracers
title_full_unstemmed	Implementation and benchmarking of a novel analytical framework to clinically evaluate tumor-specific fluorescent tracers
title_sort	implementation and benchmarking of a novel analytical framework to clinically evaluate tumor-specific fluorescent tracers
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/3ed830983e42469387cbdb1c666bbe45
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Implementation and benchmarking of a novel analytical framework to clinically evaluate tumor-specific fluorescent tracers

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