Bone marrow niche-mimetics modulate HSPC function via integrin signaling

Bone marrow niche-mimetics modulate HSPC function via integrin signaling

Abstract The bone marrow (BM) microenvironment provides critical physical cues for hematopoietic stem and progenitor cell (HSPC) maintenance and fate decision mediated by cell-matrix interactions. However, the mechanisms underlying matrix communication and signal transduction are less well understoo...

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Bibliographic Details
Main Authors: Martin Kräter, Angela Jacobi, Oliver Otto, Stefanie Tietze, Katrin Müller, David M. Poitz, Sandra Palm, Valentina M. Zinna, Ulrike Biehain, Manja Wobus, Triantafyllos Chavakis, Carsten Werner, Jochen Guck, Martin Bornhauser
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/3edcabb0611b42bd9fb7a863b22e1766
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