NAD+ pool depletion as a signal for the Rex regulon involved in Streptococcus agalactiae virulence.
In many Gram-positive bacteria, the redox-sensing transcriptional repressor Rex controls central carbon and energy metabolism by sensing the intra cellular balance between the reduced and oxidized forms of nicotinamide adenine dinucleotide; the NADH/NAD+ ratio. Here, we report high-resolution crysta...
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Autores principales: | Thierry Franza, Annika Rogstam, Saravanamuthu Thiyagarajan, Matthew J Sullivan, Aurelie Derré-Bobillot, Mikael C Bauer, Kelvin G K Goh, Violette Da Cunha, Philippe Glaser, Derek T Logan, Glen C Ulett, Claes von Wachenfeldt, Philippe Gaudu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/3ee0357565124674bb62d93dadb56787 |
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