Generation and characterization of three induced pluripotent stem cell lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) from a 51-year-old healthy individual

Skin punch biopsy was donated by a healthy 51-year-old Caucasian male and the dermal fibroblasts were reprogrammed into human induced pluripotent stem cell (hiPSC) lines by using non-integrative Sendai viruses expressing OCT4, SOX2, KLF4 and c-MYC. Three iPSC lines (NUIGi046-A, NUIGi046-B, NUIGi046-...

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Autores principales:	Min Liu, Ning Ge, Yongfeng Han, Jamie Reilly, Meimei Yang, Fan Yang, Janusz Krawczyk, Veronica McInerney, Timothy O'Brien, Terence Prendiville, Sanbing Shen
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/3ee26d29db1a45ea96ef7b75339f0cde
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spelling	oai:doaj.org-article:3ee26d29db1a45ea96ef7b75339f0cde2021-11-28T04:29:32ZGeneration and characterization of three induced pluripotent stem cell lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) from a 51-year-old healthy individual1873-506110.1016/j.scr.2021.102607https://doaj.org/article/3ee26d29db1a45ea96ef7b75339f0cde2021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1873506121004542https://doaj.org/toc/1873-5061Skin punch biopsy was donated by a healthy 51-year-old Caucasian male and the dermal fibroblasts were reprogrammed into human induced pluripotent stem cell (hiPSC) lines by using non-integrative Sendai viruses expressing OCT4, SOX2, KLF4 and c-MYC. Three iPSC lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) highly expressed the pluripotent markers and were capable of differentiating into cells of endodermal, mesodermal, and ectodermal origin. These iPSCs can be offered as controls and in combination with genome-editing and three-dimensional (3D) system. They may be used for human disease modelling and drug screening.Min LiuNing GeYongfeng HanJamie ReillyMeimei YangFan YangJanusz KrawczykVeronica McInerneyTimothy O'BrienTerence PrendivilleSanbing ShenElsevierarticleBiology (General)QH301-705.5ENStem Cell Research, Vol 57, Iss , Pp 102607- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Min Liu Ning Ge Yongfeng Han Jamie Reilly Meimei Yang Fan Yang Janusz Krawczyk Veronica McInerney Timothy O'Brien Terence Prendiville Sanbing Shen Generation and characterization of three induced pluripotent stem cell lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) from a 51-year-old healthy individual
description	Skin punch biopsy was donated by a healthy 51-year-old Caucasian male and the dermal fibroblasts were reprogrammed into human induced pluripotent stem cell (hiPSC) lines by using non-integrative Sendai viruses expressing OCT4, SOX2, KLF4 and c-MYC. Three iPSC lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) highly expressed the pluripotent markers and were capable of differentiating into cells of endodermal, mesodermal, and ectodermal origin. These iPSCs can be offered as controls and in combination with genome-editing and three-dimensional (3D) system. They may be used for human disease modelling and drug screening.
format	article
author	Min Liu Ning Ge Yongfeng Han Jamie Reilly Meimei Yang Fan Yang Janusz Krawczyk Veronica McInerney Timothy O'Brien Terence Prendiville Sanbing Shen
author_facet	Min Liu Ning Ge Yongfeng Han Jamie Reilly Meimei Yang Fan Yang Janusz Krawczyk Veronica McInerney Timothy O'Brien Terence Prendiville Sanbing Shen
author_sort	Min Liu
title	Generation and characterization of three induced pluripotent stem cell lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) from a 51-year-old healthy individual
title_short	Generation and characterization of three induced pluripotent stem cell lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) from a 51-year-old healthy individual
title_full	Generation and characterization of three induced pluripotent stem cell lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) from a 51-year-old healthy individual
title_fullStr	Generation and characterization of three induced pluripotent stem cell lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) from a 51-year-old healthy individual
title_full_unstemmed	Generation and characterization of three induced pluripotent stem cell lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) from a 51-year-old healthy individual
title_sort	generation and characterization of three induced pluripotent stem cell lines (nuigi046-a, nuigi046-b, nuigi046-c) from a 51-year-old healthy individual
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/3ee26d29db1a45ea96ef7b75339f0cde
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Generation and characterization of three induced pluripotent stem cell lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) from a 51-year-old healthy individual

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