RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions
Mammalian genomes encode tens of thousands of ncRNAs that have important roles in regulation of gene expression and chromatin organization. Here, the authors present RADICLseq to map RNA-chromatin interactions in intact nuclei to shed light on these fine-tuned processes.
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Nature Portfolio
2020
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oai:doaj.org-article:3ee35708eeee438bbb6649cdd0169ea52021-12-02T16:23:23ZRADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions10.1038/s41467-020-14337-62041-1723https://doaj.org/article/3ee35708eeee438bbb6649cdd0169ea52020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14337-6https://doaj.org/toc/2041-1723Mammalian genomes encode tens of thousands of ncRNAs that have important roles in regulation of gene expression and chromatin organization. Here, the authors present RADICLseq to map RNA-chromatin interactions in intact nuclei to shed light on these fine-tuned processes.Alessandro BonettiFederico AgostiniAna Maria SuzukiKosuke HashimotoGiovanni PascarellaJuliette GimenezLeonie RoosAlex J. NashMarco GhilottiChristopher J. F. CameronMatthew ValentineYulia A. MedvedevaShuhei NoguchiEneritz AgirreKaori KashiSamudyataJoachim LuginbühlRiccardo CazzoliSaumya AgrawalNicholas M. LuscombeMathieu BlanchetteTakeya KasukawaMichiel de HoonErik ArnerBoris LenhardCharles PlessyGonçalo Castelo-BrancoValerio OrlandoPiero CarninciNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
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DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Alessandro Bonetti Federico Agostini Ana Maria Suzuki Kosuke Hashimoto Giovanni Pascarella Juliette Gimenez Leonie Roos Alex J. Nash Marco Ghilotti Christopher J. F. Cameron Matthew Valentine Yulia A. Medvedeva Shuhei Noguchi Eneritz Agirre Kaori Kashi Samudyata Joachim Luginbühl Riccardo Cazzoli Saumya Agrawal Nicholas M. Luscombe Mathieu Blanchette Takeya Kasukawa Michiel de Hoon Erik Arner Boris Lenhard Charles Plessy Gonçalo Castelo-Branco Valerio Orlando Piero Carninci RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions |
| description |
Mammalian genomes encode tens of thousands of ncRNAs that have important roles in regulation of gene expression and chromatin organization. Here, the authors present RADICLseq to map RNA-chromatin interactions in intact nuclei to shed light on these fine-tuned processes. |
| format |
article |
| author |
Alessandro Bonetti Federico Agostini Ana Maria Suzuki Kosuke Hashimoto Giovanni Pascarella Juliette Gimenez Leonie Roos Alex J. Nash Marco Ghilotti Christopher J. F. Cameron Matthew Valentine Yulia A. Medvedeva Shuhei Noguchi Eneritz Agirre Kaori Kashi Samudyata Joachim Luginbühl Riccardo Cazzoli Saumya Agrawal Nicholas M. Luscombe Mathieu Blanchette Takeya Kasukawa Michiel de Hoon Erik Arner Boris Lenhard Charles Plessy Gonçalo Castelo-Branco Valerio Orlando Piero Carninci |
| author_facet |
Alessandro Bonetti Federico Agostini Ana Maria Suzuki Kosuke Hashimoto Giovanni Pascarella Juliette Gimenez Leonie Roos Alex J. Nash Marco Ghilotti Christopher J. F. Cameron Matthew Valentine Yulia A. Medvedeva Shuhei Noguchi Eneritz Agirre Kaori Kashi Samudyata Joachim Luginbühl Riccardo Cazzoli Saumya Agrawal Nicholas M. Luscombe Mathieu Blanchette Takeya Kasukawa Michiel de Hoon Erik Arner Boris Lenhard Charles Plessy Gonçalo Castelo-Branco Valerio Orlando Piero Carninci |
| author_sort |
Alessandro Bonetti |
| title |
RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions |
| title_short |
RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions |
| title_full |
RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions |
| title_fullStr |
RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions |
| title_full_unstemmed |
RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions |
| title_sort |
radicl-seq identifies general and cell type–specific principles of genome-wide rna-chromatin interactions |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/3ee35708eeee438bbb6649cdd0169ea5 |
| work_keys_str_mv |
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1718384105016524800 |