Unravelling the structural plasticity of stretched DNA under torsional constraint

Cellular DNA is often torsionally constrained, but the topologies that such DNA can adopt under tensile strain have remained largely untested. Here, the authors use single-molecule optical tweezers to illustrate the structural plasticity of torsionally constrained DNA under mechanical force.

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Autores principales: Graeme A. King, Erwin J. G. Peterman, Gijs J. L. Wuite
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/3ee4f21398a44e4e8bde55c6ea99e178
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spelling oai:doaj.org-article:3ee4f21398a44e4e8bde55c6ea99e1782021-12-02T17:33:22ZUnravelling the structural plasticity of stretched DNA under torsional constraint10.1038/ncomms118102041-1723https://doaj.org/article/3ee4f21398a44e4e8bde55c6ea99e1782016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11810https://doaj.org/toc/2041-1723Cellular DNA is often torsionally constrained, but the topologies that such DNA can adopt under tensile strain have remained largely untested. Here, the authors use single-molecule optical tweezers to illustrate the structural plasticity of torsionally constrained DNA under mechanical force.Graeme A. KingErwin J. G. PetermanGijs J. L. WuiteNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Graeme A. King
Erwin J. G. Peterman
Gijs J. L. Wuite
Unravelling the structural plasticity of stretched DNA under torsional constraint
description Cellular DNA is often torsionally constrained, but the topologies that such DNA can adopt under tensile strain have remained largely untested. Here, the authors use single-molecule optical tweezers to illustrate the structural plasticity of torsionally constrained DNA under mechanical force.
format article
author Graeme A. King
Erwin J. G. Peterman
Gijs J. L. Wuite
author_facet Graeme A. King
Erwin J. G. Peterman
Gijs J. L. Wuite
author_sort Graeme A. King
title Unravelling the structural plasticity of stretched DNA under torsional constraint
title_short Unravelling the structural plasticity of stretched DNA under torsional constraint
title_full Unravelling the structural plasticity of stretched DNA under torsional constraint
title_fullStr Unravelling the structural plasticity of stretched DNA under torsional constraint
title_full_unstemmed Unravelling the structural plasticity of stretched DNA under torsional constraint
title_sort unravelling the structural plasticity of stretched dna under torsional constraint
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/3ee4f21398a44e4e8bde55c6ea99e178
work_keys_str_mv AT graemeaking unravellingthestructuralplasticityofstretcheddnaundertorsionalconstraint
AT erwinjgpeterman unravellingthestructuralplasticityofstretcheddnaundertorsionalconstraint
AT gijsjlwuite unravellingthestructuralplasticityofstretcheddnaundertorsionalconstraint
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