Unravelling the structural plasticity of stretched DNA under torsional constraint
Cellular DNA is often torsionally constrained, but the topologies that such DNA can adopt under tensile strain have remained largely untested. Here, the authors use single-molecule optical tweezers to illustrate the structural plasticity of torsionally constrained DNA under mechanical force.
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Nature Portfolio
2016
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oai:doaj.org-article:3ee4f21398a44e4e8bde55c6ea99e1782021-12-02T17:33:22ZUnravelling the structural plasticity of stretched DNA under torsional constraint10.1038/ncomms118102041-1723https://doaj.org/article/3ee4f21398a44e4e8bde55c6ea99e1782016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11810https://doaj.org/toc/2041-1723Cellular DNA is often torsionally constrained, but the topologies that such DNA can adopt under tensile strain have remained largely untested. Here, the authors use single-molecule optical tweezers to illustrate the structural plasticity of torsionally constrained DNA under mechanical force.Graeme A. KingErwin J. G. PetermanGijs J. L. WuiteNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016) |
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Science Q Graeme A. King Erwin J. G. Peterman Gijs J. L. Wuite Unravelling the structural plasticity of stretched DNA under torsional constraint |
description |
Cellular DNA is often torsionally constrained, but the topologies that such DNA can adopt under tensile strain have remained largely untested. Here, the authors use single-molecule optical tweezers to illustrate the structural plasticity of torsionally constrained DNA under mechanical force. |
format |
article |
author |
Graeme A. King Erwin J. G. Peterman Gijs J. L. Wuite |
author_facet |
Graeme A. King Erwin J. G. Peterman Gijs J. L. Wuite |
author_sort |
Graeme A. King |
title |
Unravelling the structural plasticity of stretched DNA under torsional constraint |
title_short |
Unravelling the structural plasticity of stretched DNA under torsional constraint |
title_full |
Unravelling the structural plasticity of stretched DNA under torsional constraint |
title_fullStr |
Unravelling the structural plasticity of stretched DNA under torsional constraint |
title_full_unstemmed |
Unravelling the structural plasticity of stretched DNA under torsional constraint |
title_sort |
unravelling the structural plasticity of stretched dna under torsional constraint |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/3ee4f21398a44e4e8bde55c6ea99e178 |
work_keys_str_mv |
AT graemeaking unravellingthestructuralplasticityofstretcheddnaundertorsionalconstraint AT erwinjgpeterman unravellingthestructuralplasticityofstretcheddnaundertorsionalconstraint AT gijsjlwuite unravellingthestructuralplasticityofstretcheddnaundertorsionalconstraint |
_version_ |
1718379935177900032 |