Combinatorial targeting of multiple myeloma by complementing T cell engaging antibody fragments

Geis et al. investigate the potential application of hemibodies, a pair of complementary antibody fragments that redirect T cells against cancer-defining antigen combinations, such as CD38 and SLAMF7, to target multiple myeloma. Their study provides evidence that hemibodies can be developed for effe...

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Autores principales: Maria Geis, Boris Nowotny, Marc-Dominic Bohn, Dina Kouhestani, Hermann Einsele, Thomas Bumm, Gernot Stuhler
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3ee919498c4342e29413bd80927b94df
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