Characterizing rare and low-frequency height-associated variants in the Japanese population

Thousands of genetic loci are known to associate with human height, but these are mainly based on studies in European ancestry populations. Here, Akiyama et al. construct a genotype reference panel for the Japanese population followed by GWAS and report 573 height associated variants in 191,787 Japa...

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Autores principales:	Masato Akiyama, Kazuyoshi Ishigaki, Saori Sakaue, Yukihide Momozawa, Momoko Horikoshi, Makoto Hirata, Koichi Matsuda, Shiro Ikegawa, Atsushi Takahashi, Masahiro Kanai, Sadao Suzuki, Daisuke Matsui, Mariko Naito, Taiki Yamaji, Motoki Iwasaki, Norie Sawada, Kozo Tanno, Makoto Sasaki, Atsushi Hozawa, Naoko Minegishi, Kenji Wakai, Shoichiro Tsugane, Atsushi Shimizu, Masayuki Yamamoto, Yukinori Okada, Yoshinori Murakami, Michiaki Kubo, Yoichiro Kamatani
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3eeeb8172daf496ab4e694b177dd837b
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spelling	oai:doaj.org-article:3eeeb8172daf496ab4e694b177dd837b2021-12-02T15:35:33ZCharacterizing rare and low-frequency height-associated variants in the Japanese population10.1038/s41467-019-12276-52041-1723https://doaj.org/article/3eeeb8172daf496ab4e694b177dd837b2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12276-5https://doaj.org/toc/2041-1723Thousands of genetic loci are known to associate with human height, but these are mainly based on studies in European ancestry populations. Here, Akiyama et al. construct a genotype reference panel for the Japanese population followed by GWAS and report 573 height associated variants in 191,787 Japanese.Masato AkiyamaKazuyoshi IshigakiSaori SakaueYukihide MomozawaMomoko HorikoshiMakoto HirataKoichi MatsudaShiro IkegawaAtsushi TakahashiMasahiro KanaiSadao SuzukiDaisuke MatsuiMariko NaitoTaiki YamajiMotoki IwasakiNorie SawadaKozo TannoMakoto SasakiAtsushi HozawaNaoko MinegishiKenji WakaiShoichiro TsuganeAtsushi ShimizuMasayuki YamamotoYukinori OkadaYoshinori MurakamiMichiaki KuboYoichiro KamataniNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Masato Akiyama Kazuyoshi Ishigaki Saori Sakaue Yukihide Momozawa Momoko Horikoshi Makoto Hirata Koichi Matsuda Shiro Ikegawa Atsushi Takahashi Masahiro Kanai Sadao Suzuki Daisuke Matsui Mariko Naito Taiki Yamaji Motoki Iwasaki Norie Sawada Kozo Tanno Makoto Sasaki Atsushi Hozawa Naoko Minegishi Kenji Wakai Shoichiro Tsugane Atsushi Shimizu Masayuki Yamamoto Yukinori Okada Yoshinori Murakami Michiaki Kubo Yoichiro Kamatani Characterizing rare and low-frequency height-associated variants in the Japanese population
description	Thousands of genetic loci are known to associate with human height, but these are mainly based on studies in European ancestry populations. Here, Akiyama et al. construct a genotype reference panel for the Japanese population followed by GWAS and report 573 height associated variants in 191,787 Japanese.
format	article
author	Masato Akiyama Kazuyoshi Ishigaki Saori Sakaue Yukihide Momozawa Momoko Horikoshi Makoto Hirata Koichi Matsuda Shiro Ikegawa Atsushi Takahashi Masahiro Kanai Sadao Suzuki Daisuke Matsui Mariko Naito Taiki Yamaji Motoki Iwasaki Norie Sawada Kozo Tanno Makoto Sasaki Atsushi Hozawa Naoko Minegishi Kenji Wakai Shoichiro Tsugane Atsushi Shimizu Masayuki Yamamoto Yukinori Okada Yoshinori Murakami Michiaki Kubo Yoichiro Kamatani
author_facet	Masato Akiyama Kazuyoshi Ishigaki Saori Sakaue Yukihide Momozawa Momoko Horikoshi Makoto Hirata Koichi Matsuda Shiro Ikegawa Atsushi Takahashi Masahiro Kanai Sadao Suzuki Daisuke Matsui Mariko Naito Taiki Yamaji Motoki Iwasaki Norie Sawada Kozo Tanno Makoto Sasaki Atsushi Hozawa Naoko Minegishi Kenji Wakai Shoichiro Tsugane Atsushi Shimizu Masayuki Yamamoto Yukinori Okada Yoshinori Murakami Michiaki Kubo Yoichiro Kamatani
author_sort	Masato Akiyama
title	Characterizing rare and low-frequency height-associated variants in the Japanese population
title_short	Characterizing rare and low-frequency height-associated variants in the Japanese population
title_full	Characterizing rare and low-frequency height-associated variants in the Japanese population
title_fullStr	Characterizing rare and low-frequency height-associated variants in the Japanese population
title_full_unstemmed	Characterizing rare and low-frequency height-associated variants in the Japanese population
title_sort	characterizing rare and low-frequency height-associated variants in the japanese population
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/3eeeb8172daf496ab4e694b177dd837b
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Characterizing rare and low-frequency height-associated variants in the Japanese population

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