Three-dimensional structural dynamics and fluctuations of DNA-nanogold conjugates by individual-particle electron tomography

The control of DNA-mediated assembly depends on a precise understanding of the three-dimensional structure of DNA-nanocrystal-hybridized building blocks. Here, the authors use cryo-electron microscopy and negative-staining techniques to investigate the morphology of DNA-nanogold conjugates.

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Autores principales: Lei Zhang, Dongsheng Lei, Jessica M. Smith, Meng Zhang, Huimin Tong, Xing Zhang, Zhuoyang Lu, Jiankang Liu, A. Paul Alivisatos, Gang Ren
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/3ef480a691aa40cdb14b8d3664927fb2
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spelling oai:doaj.org-article:3ef480a691aa40cdb14b8d3664927fb22021-12-02T15:35:00ZThree-dimensional structural dynamics and fluctuations of DNA-nanogold conjugates by individual-particle electron tomography10.1038/ncomms110832041-1723https://doaj.org/article/3ef480a691aa40cdb14b8d3664927fb22016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11083https://doaj.org/toc/2041-1723The control of DNA-mediated assembly depends on a precise understanding of the three-dimensional structure of DNA-nanocrystal-hybridized building blocks. Here, the authors use cryo-electron microscopy and negative-staining techniques to investigate the morphology of DNA-nanogold conjugates.Lei ZhangDongsheng LeiJessica M. SmithMeng ZhangHuimin TongXing ZhangZhuoyang LuJiankang LiuA. Paul AlivisatosGang RenNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lei Zhang
Dongsheng Lei
Jessica M. Smith
Meng Zhang
Huimin Tong
Xing Zhang
Zhuoyang Lu
Jiankang Liu
A. Paul Alivisatos
Gang Ren
Three-dimensional structural dynamics and fluctuations of DNA-nanogold conjugates by individual-particle electron tomography
description The control of DNA-mediated assembly depends on a precise understanding of the three-dimensional structure of DNA-nanocrystal-hybridized building blocks. Here, the authors use cryo-electron microscopy and negative-staining techniques to investigate the morphology of DNA-nanogold conjugates.
format article
author Lei Zhang
Dongsheng Lei
Jessica M. Smith
Meng Zhang
Huimin Tong
Xing Zhang
Zhuoyang Lu
Jiankang Liu
A. Paul Alivisatos
Gang Ren
author_facet Lei Zhang
Dongsheng Lei
Jessica M. Smith
Meng Zhang
Huimin Tong
Xing Zhang
Zhuoyang Lu
Jiankang Liu
A. Paul Alivisatos
Gang Ren
author_sort Lei Zhang
title Three-dimensional structural dynamics and fluctuations of DNA-nanogold conjugates by individual-particle electron tomography
title_short Three-dimensional structural dynamics and fluctuations of DNA-nanogold conjugates by individual-particle electron tomography
title_full Three-dimensional structural dynamics and fluctuations of DNA-nanogold conjugates by individual-particle electron tomography
title_fullStr Three-dimensional structural dynamics and fluctuations of DNA-nanogold conjugates by individual-particle electron tomography
title_full_unstemmed Three-dimensional structural dynamics and fluctuations of DNA-nanogold conjugates by individual-particle electron tomography
title_sort three-dimensional structural dynamics and fluctuations of dna-nanogold conjugates by individual-particle electron tomography
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/3ef480a691aa40cdb14b8d3664927fb2
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