Rap1 can bypass the FAK-Src-Paxillin cascade to induce cell spreading and focal adhesion formation.
We developed new image analysis tools to analyse quantitatively the extracellular-matrix-dependent cell spreading process imaged by live-cell epifluorescence microscopy. Using these tools, we investigated cell spreading induced by activation of the small GTPase, Rap1. After replating and initial adh...
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Auteurs principaux: | Sarah H Ross, Emma Spanjaard, Anneke Post, Marjolein J Vliem, Hendy Kristyanto, Johannes L Bos, Johan de Rooij |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2012
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Accès en ligne: | https://doaj.org/article/3ef73f727ea84a80bc37a1e8f771963e |
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