Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis

The sequence of structural and molecular events during clathrin-mediated endocytosis is unclear. Here the authors combine correlative microscopy and simple mathematical growth laws to demonstrate that the flat patch starts to curve when around 70% of the final clathrin content is reached.

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Autores principales:	Delia Bucher, Felix Frey, Kem A. Sochacki, Susann Kummer, Jan-Philip Bergeest, William J. Godinez, Hans-Georg Kräusslich, Karl Rohr, Justin W. Taraska, Ulrich S. Schwarz, Steeve Boulant
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3f0780a0131e44ce8d01e1cb3d81a9e5
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spelling	oai:doaj.org-article:3f0780a0131e44ce8d01e1cb3d81a9e52021-12-02T16:56:42ZClathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis10.1038/s41467-018-03533-02041-1723https://doaj.org/article/3f0780a0131e44ce8d01e1cb3d81a9e52018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03533-0https://doaj.org/toc/2041-1723The sequence of structural and molecular events during clathrin-mediated endocytosis is unclear. Here the authors combine correlative microscopy and simple mathematical growth laws to demonstrate that the flat patch starts to curve when around 70% of the final clathrin content is reached.Delia BucherFelix FreyKem A. SochackiSusann KummerJan-Philip BergeestWilliam J. GodinezHans-Georg KräusslichKarl RohrJustin W. TaraskaUlrich S. SchwarzSteeve BoulantNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Delia Bucher Felix Frey Kem A. Sochacki Susann Kummer Jan-Philip Bergeest William J. Godinez Hans-Georg Kräusslich Karl Rohr Justin W. Taraska Ulrich S. Schwarz Steeve Boulant Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis
description	The sequence of structural and molecular events during clathrin-mediated endocytosis is unclear. Here the authors combine correlative microscopy and simple mathematical growth laws to demonstrate that the flat patch starts to curve when around 70% of the final clathrin content is reached.
format	article
author	Delia Bucher Felix Frey Kem A. Sochacki Susann Kummer Jan-Philip Bergeest William J. Godinez Hans-Georg Kräusslich Karl Rohr Justin W. Taraska Ulrich S. Schwarz Steeve Boulant
author_facet	Delia Bucher Felix Frey Kem A. Sochacki Susann Kummer Jan-Philip Bergeest William J. Godinez Hans-Georg Kräusslich Karl Rohr Justin W. Taraska Ulrich S. Schwarz Steeve Boulant
author_sort	Delia Bucher
title	Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis
title_short	Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis
title_full	Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis
title_fullStr	Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis
title_full_unstemmed	Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis
title_sort	clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/3f0780a0131e44ce8d01e1cb3d81a9e5
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Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis

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