Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis
The sequence of structural and molecular events during clathrin-mediated endocytosis is unclear. Here the authors combine correlative microscopy and simple mathematical growth laws to demonstrate that the flat patch starts to curve when around 70% of the final clathrin content is reached.
Guardado en:
Autores principales: | Delia Bucher, Felix Frey, Kem A. Sochacki, Susann Kummer, Jan-Philip Bergeest, William J. Godinez, Hans-Georg Kräusslich, Karl Rohr, Justin W. Taraska, Ulrich S. Schwarz, Steeve Boulant |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/3f0780a0131e44ce8d01e1cb3d81a9e5 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors
por: Daniela Leyton-Puig, et al.
Publicado: (2017) -
Sterols lower energetic barriers of membrane bending and fission necessary for efficient clathrin-mediated endocytosis
por: Ruthellen H. Anderson, et al.
Publicado: (2021) -
Structure of the endocytic adaptor complex reveals the basis for efficient membrane anchoring during clathrin-mediated endocytosis
por: Javier Lizarrondo, et al.
Publicado: (2021) -
Endocytosis of HERG is clathrin-independent and involves arf6.
por: Rucha Karnik, et al.
Publicado: (2013) -
Clostridial glucosylating toxins enter cells via clathrin-mediated endocytosis.
por: Panagiotis Papatheodorou, et al.
Publicado: (2010)