Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme

Twister-sister is a self-cleaving ribozyme. Here, the authors report the 2.0 Å crystal structure of the four-way junctional twister-sister ribozyme in the pre-catalytic state and discuss mechanistic implications based on their mutagenesis experiments and comparisons with other ribozyme structures....

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Auteurs principaux: Luqian Zheng, Elisabeth Mairhofer, Marianna Teplova, Ye Zhang, Jinbiao Ma, Dinshaw J. Patel, Ronald Micura, Aiming Ren
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/3f0c978cdb61435a9e3fd422ad02ce2f
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