Pixelated spatial gene expression analysis from tissue

Pixelated spatial gene expression analysis from tissue

Spatial localization of genetic information is important for tissue heterogeneity but difficult to capture with current analytical techniques. Here the authors present “Pixelated RT-LAMP”, an approach that uses parallel on-chip reactions to provide the distribution of target sequences directly from...

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Autores principales: A. Ganguli, A. Ornob, N. Spegazzini, Y. Liu, G. Damhorst, T. Ghonge, B. Thornton, C. J. Konopka, W. Dobrucki, S. E. Clare, R. Bhargava, A. M. Smith, F. Kosari, R. Bashir
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Q
Acceso en línea:https://doaj.org/article/3f0ffa80cb5a4920885a266e00c14507
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spelling oai:doaj.org-article:3f0ffa80cb5a4920885a266e00c145072021-12-02T14:40:31ZPixelated spatial gene expression analysis from tissue10.1038/s41467-017-02623-92041-1723https://doaj.org/article/3f0ffa80cb5a4920885a266e00c145072018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02623-9https://doaj.org/toc/2041-1723Spatial localization of genetic information is important for tissue heterogeneity but difficult to capture with current analytical techniques. Here the authors present “Pixelated RT-LAMP”, an approach that uses parallel on-chip reactions to provide the distribution of target sequences directly from tissue.A. GanguliA. OrnobN. SpegazziniY. LiuG. DamhorstT. GhongeB. ThorntonC. J. KonopkaW. DobruckiS. E. ClareR. BhargavaA. M. SmithF. KosariR. BashirNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
A. Ganguli
A. Ornob
N. Spegazzini
Y. Liu
G. Damhorst
T. Ghonge
B. Thornton
C. J. Konopka
W. Dobrucki
S. E. Clare
R. Bhargava
A. M. Smith
F. Kosari
R. Bashir
Pixelated spatial gene expression analysis from tissue
description Spatial localization of genetic information is important for tissue heterogeneity but difficult to capture with current analytical techniques. Here the authors present “Pixelated RT-LAMP”, an approach that uses parallel on-chip reactions to provide the distribution of target sequences directly from tissue.
format article
author A. Ganguli
A. Ornob
N. Spegazzini
Y. Liu
G. Damhorst
T. Ghonge
B. Thornton
C. J. Konopka
W. Dobrucki
S. E. Clare
R. Bhargava
A. M. Smith
F. Kosari
R. Bashir
author_facet A. Ganguli
A. Ornob
N. Spegazzini
Y. Liu
G. Damhorst
T. Ghonge
B. Thornton
C. J. Konopka
W. Dobrucki
S. E. Clare
R. Bhargava
A. M. Smith
F. Kosari
R. Bashir
author_sort A. Ganguli
title Pixelated spatial gene expression analysis from tissue
title_short Pixelated spatial gene expression analysis from tissue
title_full Pixelated spatial gene expression analysis from tissue
title_fullStr Pixelated spatial gene expression analysis from tissue
title_full_unstemmed Pixelated spatial gene expression analysis from tissue
title_sort pixelated spatial gene expression analysis from tissue
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/3f0ffa80cb5a4920885a266e00c14507
work_keys_str_mv AT aganguli pixelatedspatialgeneexpressionanalysisfromtissue
AT aornob pixelatedspatialgeneexpressionanalysisfromtissue
AT nspegazzini pixelatedspatialgeneexpressionanalysisfromtissue
AT yliu pixelatedspatialgeneexpressionanalysisfromtissue
AT gdamhorst pixelatedspatialgeneexpressionanalysisfromtissue
AT tghonge pixelatedspatialgeneexpressionanalysisfromtissue
AT bthornton pixelatedspatialgeneexpressionanalysisfromtissue
AT cjkonopka pixelatedspatialgeneexpressionanalysisfromtissue
AT wdobrucki pixelatedspatialgeneexpressionanalysisfromtissue
AT seclare pixelatedspatialgeneexpressionanalysisfromtissue
AT rbhargava pixelatedspatialgeneexpressionanalysisfromtissue
AT amsmith pixelatedspatialgeneexpressionanalysisfromtissue
AT fkosari pixelatedspatialgeneexpressionanalysisfromtissue
AT rbashir pixelatedspatialgeneexpressionanalysisfromtissue
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