Retinal breaks due to intravitreal ocriplasmin

Ruwan A Silva, Darius M Moshfeghi, Theodore Leng Byers Eye Institute at Stanford, Stanford University School of Medicine, Palo Alto, CA, USA Abstract: Ocriplasmin represents a new treatment option for numerous vitreoretinopathies involving an abnormal vitreomacular interface. While the drug may c...

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Autores principales:	Silva RA, Moshfeghi DM, Leng T
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/3f1d3110abfc4a79a69b6a8a3353c680
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spelling	oai:doaj.org-article:3f1d3110abfc4a79a69b6a8a3353c6802021-12-02T02:55:34ZRetinal breaks due to intravitreal ocriplasmin1177-5483https://doaj.org/article/3f1d3110abfc4a79a69b6a8a3353c6802014-08-01T00:00:00Zhttp://www.dovepress.com/retinal-breaks-due-to-intravitreal-ocriplasmin-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483 Ruwan A Silva, Darius M Moshfeghi, Theodore Leng Byers Eye Institute at Stanford, Stanford University School of Medicine, Palo Alto, CA, USA Abstract: Ocriplasmin represents a new treatment option for numerous vitreoretinopathies involving an abnormal vitreomacular interface. While the drug may circumvent the traditional risks of surgical treatment, pharmacologic vitreolysis is not devoid of risk itself. This report presents two cases, one of vitreomacular traction syndrome and the other of a full-thickness macular hole, both of which were treated with an intravitreal injection of ocriplasmin. Notably, in both cases, vitreomacular traction of the macula appears to have been alleviated; however, failure to completely relieve vitreoretinal traction from the peripheral retina generated retinal breaks with one patient eventually developing a macula-involving retinal detachment. Thus, even in instances of ‘successful’ pharmacologic treatment of vitreomacular traction, continued follow-up evaluation is essential. Keywords: posterior vitreous detachment, retinal detachment, vitreomacular traction, ocriplasmin, retinal break, macular hole, laser retinopexySilva RAMoshfeghi DMLeng TDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2014, Iss default, Pp 1591-1594 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Silva RA Moshfeghi DM Leng T Retinal breaks due to intravitreal ocriplasmin
description	Ruwan A Silva, Darius M Moshfeghi, Theodore Leng Byers Eye Institute at Stanford, Stanford University School of Medicine, Palo Alto, CA, USA Abstract: Ocriplasmin represents a new treatment option for numerous vitreoretinopathies involving an abnormal vitreomacular interface. While the drug may circumvent the traditional risks of surgical treatment, pharmacologic vitreolysis is not devoid of risk itself. This report presents two cases, one of vitreomacular traction syndrome and the other of a full-thickness macular hole, both of which were treated with an intravitreal injection of ocriplasmin. Notably, in both cases, vitreomacular traction of the macula appears to have been alleviated; however, failure to completely relieve vitreoretinal traction from the peripheral retina generated retinal breaks with one patient eventually developing a macula-involving retinal detachment. Thus, even in instances of ‘successful’ pharmacologic treatment of vitreomacular traction, continued follow-up evaluation is essential. Keywords: posterior vitreous detachment, retinal detachment, vitreomacular traction, ocriplasmin, retinal break, macular hole, laser retinopexy
format	article
author	Silva RA Moshfeghi DM Leng T
author_facet	Silva RA Moshfeghi DM Leng T
author_sort	Silva RA
title	Retinal breaks due to intravitreal ocriplasmin
title_short	Retinal breaks due to intravitreal ocriplasmin
title_full	Retinal breaks due to intravitreal ocriplasmin
title_fullStr	Retinal breaks due to intravitreal ocriplasmin
title_full_unstemmed	Retinal breaks due to intravitreal ocriplasmin
title_sort	retinal breaks due to intravitreal ocriplasmin
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/3f1d3110abfc4a79a69b6a8a3353c680
work_keys_str_mv	AT silvara retinalbreaksduetointravitrealocriplasmin AT moshfeghidm retinalbreaksduetointravitrealocriplasmin AT lengt retinalbreaksduetointravitrealocriplasmin
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Retinal breaks due to intravitreal ocriplasmin

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