Calcium stabilizes the strongest protein fold

Staphylococcal pathogens adhere to their human targets using adhesins, which can withstand extremely high forces. Here, authors use single-molecule force spectroscopy to determine the similarly high unfolding forces of B domains that link the adhesin to the bacterium.

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Bibliographic Details
Main Authors: Lukas F. Milles, Eduard M. Unterauer, Thomas Nicolaus, Hermann E. Gaub
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/3f2523c006d44bfc9a24d45ca7291cb5
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