Calcium stabilizes the strongest protein fold
Staphylococcal pathogens adhere to their human targets using adhesins, which can withstand extremely high forces. Here, authors use single-molecule force spectroscopy to determine the similarly high unfolding forces of B domains that link the adhesin to the bacterium.
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Main Authors: | Lukas F. Milles, Eduard M. Unterauer, Thomas Nicolaus, Hermann E. Gaub |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Subjects: | |
Online Access: | https://doaj.org/article/3f2523c006d44bfc9a24d45ca7291cb5 |
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