Genetic breakdown of a Tet-off conditional lethality system for insect population control

Insect population control using conditional lethal systems could break down due to spontaneous mutations that render the system ineffective. Here the authors analyse the structure and frequency of such mutations in Drosophila and suggest the use of dual lethality systems to mitigate their survival.

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Autores principales:	Yang Zhao, Marc F. Schetelig, Alfred M. Handler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3f2c7fefb5b84e65badf546a223c11ef
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spelling	oai:doaj.org-article:3f2c7fefb5b84e65badf546a223c11ef2021-12-02T17:40:35ZGenetic breakdown of a Tet-off conditional lethality system for insect population control10.1038/s41467-020-16807-32041-1723https://doaj.org/article/3f2c7fefb5b84e65badf546a223c11ef2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16807-3https://doaj.org/toc/2041-1723Insect population control using conditional lethal systems could break down due to spontaneous mutations that render the system ineffective. Here the authors analyse the structure and frequency of such mutations in Drosophila and suggest the use of dual lethality systems to mitigate their survival.Yang ZhaoMarc F. ScheteligAlfred M. HandlerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yang Zhao Marc F. Schetelig Alfred M. Handler Genetic breakdown of a Tet-off conditional lethality system for insect population control
description	Insect population control using conditional lethal systems could break down due to spontaneous mutations that render the system ineffective. Here the authors analyse the structure and frequency of such mutations in Drosophila and suggest the use of dual lethality systems to mitigate their survival.
format	article
author	Yang Zhao Marc F. Schetelig Alfred M. Handler
author_facet	Yang Zhao Marc F. Schetelig Alfred M. Handler
author_sort	Yang Zhao
title	Genetic breakdown of a Tet-off conditional lethality system for insect population control
title_short	Genetic breakdown of a Tet-off conditional lethality system for insect population control
title_full	Genetic breakdown of a Tet-off conditional lethality system for insect population control
title_fullStr	Genetic breakdown of a Tet-off conditional lethality system for insect population control
title_full_unstemmed	Genetic breakdown of a Tet-off conditional lethality system for insect population control
title_sort	genetic breakdown of a tet-off conditional lethality system for insect population control
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/3f2c7fefb5b84e65badf546a223c11ef
work_keys_str_mv	AT yangzhao geneticbreakdownofatetoffconditionallethalitysystemforinsectpopulationcontrol AT marcfschetelig geneticbreakdownofatetoffconditionallethalitysystemforinsectpopulationcontrol AT alfredmhandler geneticbreakdownofatetoffconditionallethalitysystemforinsectpopulationcontrol
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Genetic breakdown of a Tet-off conditional lethality system for insect population control

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