Comparative AAPOS Validation of the Birefringent Amblyopia Screener with Isolated Small-Angle Strabismus

Robert W Arnold Alaska Blind Child Discovery, Alaska Children’s Eye and Strabismus, Anchorage, AK, USACorrespondence: Robert W ArnoldAlaska Blind Child Discovery, Alaska Children’s Eye and Strabismus, 3500 Latouche #280, Anchorage, AK 99508, USATel +1 907 561-1917Fax +1 907 563-5...

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Autor principal:	Arnold RW
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	birefringent photoscreening amblyopia fixation instability amblyopia risk factor strabismus Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/3f2e5ce4ff2140289768dc43f2a61848
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spelling	oai:doaj.org-article:3f2e5ce4ff2140289768dc43f2a618482021-12-02T11:18:39ZComparative AAPOS Validation of the Birefringent Amblyopia Screener with Isolated Small-Angle Strabismus1177-5483https://doaj.org/article/3f2e5ce4ff2140289768dc43f2a618482020-01-01T00:00:00Zhttps://www.dovepress.com/comparative-aapos-validation-of-the-birefringent-amblyopia-screener-wi-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Robert W Arnold Alaska Blind Child Discovery, Alaska Children’s Eye and Strabismus, Anchorage, AK, USACorrespondence: Robert W ArnoldAlaska Blind Child Discovery, Alaska Children’s Eye and Strabismus, 3500 Latouche #280, Anchorage, AK 99508, USATel +1 907 561-1917Fax +1 907 563-5373Email eyedoc@alaska.netBackground: The Rebion blinq binocular birefringent ocular alignment screener was recently commercially released, but it did not yet have validation by American Association for Pediatric Ophthalmology and Strabismus (AAPOS) uniform guidelines.Methods: Children and adults from a high-risk eye practice had screening by blinq with validation by AAPOS 2003 guidelines. Then, the blinq was compared to the Adaptica 2WIN with CR corneal reflex strabismus estimation by AAPOS 2003 guidelines plus additional efforts to identify patients with diminished binocularity.Results: Blinq in 100 patients compared to 2003 AAPOS amblyopia risk factors (ARF) had sensitivity 67%, specificity 75% and PPV of 82%. Both blinq and 2WIN were completed by 87 patients median age 6.5 years. Sensitivity, specificity and positive predictive value (PPV) for blinq were 75%, 68% and 81% whereas 2WIN had 91%, 68% and 84%. The blinq referred two young patients with isolated, small-angle strabismic amblyopia that 2WIN refractive function passed.Conclusion: Despite its non-refractive design to identify binocular foveation, blinq performed well with refractive and strabismic uniform risk factors and a PPV greater than 80%.Clinical Trials Registry: NCT04195711.Keywords: birefringent, photoscreening, amblyopia, fixation instability, amblyopia risk factor, strabismusArnold RWDove Medical Pressarticlebirefringentphotoscreeningamblyopiafixation instabilityamblyopia risk factorstrabismusOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 325-329 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	birefringent photoscreening amblyopia fixation instability amblyopia risk factor strabismus Ophthalmology RE1-994
spellingShingle	birefringent photoscreening amblyopia fixation instability amblyopia risk factor strabismus Ophthalmology RE1-994 Arnold RW Comparative AAPOS Validation of the Birefringent Amblyopia Screener with Isolated Small-Angle Strabismus
description	Robert W Arnold Alaska Blind Child Discovery, Alaska Children’s Eye and Strabismus, Anchorage, AK, USACorrespondence: Robert W ArnoldAlaska Blind Child Discovery, Alaska Children’s Eye and Strabismus, 3500 Latouche #280, Anchorage, AK 99508, USATel +1 907 561-1917Fax +1 907 563-5373Email eyedoc@alaska.netBackground: The Rebion blinq binocular birefringent ocular alignment screener was recently commercially released, but it did not yet have validation by American Association for Pediatric Ophthalmology and Strabismus (AAPOS) uniform guidelines.Methods: Children and adults from a high-risk eye practice had screening by blinq with validation by AAPOS 2003 guidelines. Then, the blinq was compared to the Adaptica 2WIN with CR corneal reflex strabismus estimation by AAPOS 2003 guidelines plus additional efforts to identify patients with diminished binocularity.Results: Blinq in 100 patients compared to 2003 AAPOS amblyopia risk factors (ARF) had sensitivity 67%, specificity 75% and PPV of 82%. Both blinq and 2WIN were completed by 87 patients median age 6.5 years. Sensitivity, specificity and positive predictive value (PPV) for blinq were 75%, 68% and 81% whereas 2WIN had 91%, 68% and 84%. The blinq referred two young patients with isolated, small-angle strabismic amblyopia that 2WIN refractive function passed.Conclusion: Despite its non-refractive design to identify binocular foveation, blinq performed well with refractive and strabismic uniform risk factors and a PPV greater than 80%.Clinical Trials Registry: NCT04195711.Keywords: birefringent, photoscreening, amblyopia, fixation instability, amblyopia risk factor, strabismus
format	article
author	Arnold RW
author_facet	Arnold RW
author_sort	Arnold RW
title	Comparative AAPOS Validation of the Birefringent Amblyopia Screener with Isolated Small-Angle Strabismus
title_short	Comparative AAPOS Validation of the Birefringent Amblyopia Screener with Isolated Small-Angle Strabismus
title_full	Comparative AAPOS Validation of the Birefringent Amblyopia Screener with Isolated Small-Angle Strabismus
title_fullStr	Comparative AAPOS Validation of the Birefringent Amblyopia Screener with Isolated Small-Angle Strabismus
title_full_unstemmed	Comparative AAPOS Validation of the Birefringent Amblyopia Screener with Isolated Small-Angle Strabismus
title_sort	comparative aapos validation of the birefringent amblyopia screener with isolated small-angle strabismus
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/3f2e5ce4ff2140289768dc43f2a61848
work_keys_str_mv	AT arnoldrw comparativeaaposvalidationofthebirefringentamblyopiascreenerwithisolatedsmallanglestrabismus
_version_	1718395988215857152

Comparative AAPOS Validation of the Birefringent Amblyopia Screener with Isolated Small-Angle Strabismus

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