Neutrophils are resistant to Yersinia YopJ/P-induced apoptosis and are protected from ROS-mediated cell death by the type III secretion system.
<h4>Background</h4>The human innate immune system relies on the coordinated activity of macrophages and polymorphonuclear leukocytes (neutrophils or PMNs) for defense against bacterial pathogens. Yersinia spp. subvert the innate immune response to cause disease in humans. In particular,...
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Main Authors: | Justin L Spinner, Keun Seok Seo, Jason L O'Loughlin, Jennifer A Cundiff, Scott A Minnich, Gregory A Bohach, Scott D Kobayashi |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2010
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Online Access: | https://doaj.org/article/3f5147da69a249e9a95227c3368a268c |
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