The influence of comorbid personality disorders on recovery from depression

Tinakon Wongpakaran, Nahathai Wongpakaran, Vudhichai Boonyanaruthee, Manee Pinyopornpanish, Suthi Intaprasert Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Purpose: The impact of personality disorders on the treatment of and recovery from depression is...

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Autores principales: Wongpakaran T, Wongpakaran N, Boonyanaruthee V, Pinyopornpanish M, Intaprasert S
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2015
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spelling oai:doaj.org-article:3f552304b3524beebc11e560598f79ef2021-12-02T00:43:05ZThe influence of comorbid personality disorders on recovery from depression1178-2021https://doaj.org/article/3f552304b3524beebc11e560598f79ef2015-03-01T00:00:00Zhttp://www.dovepress.com/the-influence-of-comorbid-personality-disorders-on-recovery-from-depre-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021 Tinakon Wongpakaran, Nahathai Wongpakaran, Vudhichai Boonyanaruthee, Manee Pinyopornpanish, Suthi Intaprasert Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Purpose: The impact of personality disorders on the treatment of and recovery from depression is still a controversial topic. The aim of this paper is to provide more information on what has led to this disagreement.Materials and methods: Clinician-rated Hamilton Depression Rating Scale (HAMD) scores were assessed among 82 depressed outpatients who were receiving a routine treatment combination of antidepressant medication and psychosocial intervention. The participants were followed up over five visits at 3-month intervals: at the baseline, at 3, 6, 9 and 12 months. Personality disorders were assessed after the last visit in accordance with Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. These repeated measures were used to explore the impact of personality disorders on HAMD scores by using a linear mixed model.Results: Among the four personality clusters that were used (A, B, C, and mixed), only those in cluster B and in the mixed cluster were found to take significantly longer than those without personality disorders, for reduction in HAMD scores over the course of treatment.Conclusion: In this study, the impact of personality disorders on treatment outcomes varied with the way that the personality disorder variables were described and used as independent predictors. This is because the outcomes were influenced by the impact weight of each personality disorder, even within the same cluster. Keywords: depressive disorder, mixed linear model, impact, multilevel analysisWongpakaran TWongpakaran NBoonyanaruthee VPinyopornpanish MIntaprasert SDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2015, Iss default, Pp 725-732 (2015)
institution DOAJ
collection DOAJ
language EN
topic Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Wongpakaran T
Wongpakaran N
Boonyanaruthee V
Pinyopornpanish M
Intaprasert S
The influence of comorbid personality disorders on recovery from depression
description Tinakon Wongpakaran, Nahathai Wongpakaran, Vudhichai Boonyanaruthee, Manee Pinyopornpanish, Suthi Intaprasert Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Purpose: The impact of personality disorders on the treatment of and recovery from depression is still a controversial topic. The aim of this paper is to provide more information on what has led to this disagreement.Materials and methods: Clinician-rated Hamilton Depression Rating Scale (HAMD) scores were assessed among 82 depressed outpatients who were receiving a routine treatment combination of antidepressant medication and psychosocial intervention. The participants were followed up over five visits at 3-month intervals: at the baseline, at 3, 6, 9 and 12 months. Personality disorders were assessed after the last visit in accordance with Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. These repeated measures were used to explore the impact of personality disorders on HAMD scores by using a linear mixed model.Results: Among the four personality clusters that were used (A, B, C, and mixed), only those in cluster B and in the mixed cluster were found to take significantly longer than those without personality disorders, for reduction in HAMD scores over the course of treatment.Conclusion: In this study, the impact of personality disorders on treatment outcomes varied with the way that the personality disorder variables were described and used as independent predictors. This is because the outcomes were influenced by the impact weight of each personality disorder, even within the same cluster. Keywords: depressive disorder, mixed linear model, impact, multilevel analysis
format article
author Wongpakaran T
Wongpakaran N
Boonyanaruthee V
Pinyopornpanish M
Intaprasert S
author_facet Wongpakaran T
Wongpakaran N
Boonyanaruthee V
Pinyopornpanish M
Intaprasert S
author_sort Wongpakaran T
title The influence of comorbid personality disorders on recovery from depression
title_short The influence of comorbid personality disorders on recovery from depression
title_full The influence of comorbid personality disorders on recovery from depression
title_fullStr The influence of comorbid personality disorders on recovery from depression
title_full_unstemmed The influence of comorbid personality disorders on recovery from depression
title_sort influence of comorbid personality disorders on recovery from depression
publisher Dove Medical Press
publishDate 2015
url https://doaj.org/article/3f552304b3524beebc11e560598f79ef
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