Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores

SNAREs mediate the formation of a fusion pore during exocytosis which connects the lumen of a vesicle with the extracellular space. Here, authors use single molecule approaches to define the role of synaptotagmin 1 and NSF in synaptic pore formation and dissolution.

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Autores principales:	Debasis Das, Huan Bao, Kevin C. Courtney, Lanxi Wu, Edwin R. Chapman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3f5a1f5773cd4fc6a794f2fc8bf7582b
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spelling	oai:doaj.org-article:3f5a1f5773cd4fc6a794f2fc8bf7582b2021-12-02T17:32:14ZResolving kinetic intermediates during the regulated assembly and disassembly of fusion pores10.1038/s41467-019-14072-72041-1723https://doaj.org/article/3f5a1f5773cd4fc6a794f2fc8bf7582b2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14072-7https://doaj.org/toc/2041-1723SNAREs mediate the formation of a fusion pore during exocytosis which connects the lumen of a vesicle with the extracellular space. Here, authors use single molecule approaches to define the role of synaptotagmin 1 and NSF in synaptic pore formation and dissolution.Debasis DasHuan BaoKevin C. CourtneyLanxi WuEdwin R. ChapmanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Debasis Das Huan Bao Kevin C. Courtney Lanxi Wu Edwin R. Chapman Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores
description	SNAREs mediate the formation of a fusion pore during exocytosis which connects the lumen of a vesicle with the extracellular space. Here, authors use single molecule approaches to define the role of synaptotagmin 1 and NSF in synaptic pore formation and dissolution.
format	article
author	Debasis Das Huan Bao Kevin C. Courtney Lanxi Wu Edwin R. Chapman
author_facet	Debasis Das Huan Bao Kevin C. Courtney Lanxi Wu Edwin R. Chapman
author_sort	Debasis Das
title	Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores
title_short	Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores
title_full	Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores
title_fullStr	Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores
title_full_unstemmed	Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores
title_sort	resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/3f5a1f5773cd4fc6a794f2fc8bf7582b
work_keys_str_mv	AT debasisdas resolvingkineticintermediatesduringtheregulatedassemblyanddisassemblyoffusionpores AT huanbao resolvingkineticintermediatesduringtheregulatedassemblyanddisassemblyoffusionpores AT kevinccourtney resolvingkineticintermediatesduringtheregulatedassemblyanddisassemblyoffusionpores AT lanxiwu resolvingkineticintermediatesduringtheregulatedassemblyanddisassemblyoffusionpores AT edwinrchapman resolvingkineticintermediatesduringtheregulatedassemblyanddisassemblyoffusionpores
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Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores

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