Separate developmental programs for HLA-A and -B cell surface expression during differentiation from embryonic stem cells to lymphocytes, adipocytes and osteoblasts.
A major problem of allogeneic stem cell therapy is immunologically mediated graft rejection. HLA class I A, B, and Cw antigens are crucial factors, but little is known of their respective expression on stem cells and their progenies. We have recently shown that locus-specific expression (HLA-A, but...
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Main Authors: | Hardee J Sabir, Jan O Nehlin, Diyako Qanie, Linda Harkness, Tatyana A Prokhorova, Blagoy Blagoev, Moustapha Kassem, Adiba Isa, Torben Barington |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Subjects: | |
Online Access: | https://doaj.org/article/3f628e9ff4de49a59f4b88791e5da8bd |
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