Quantitative phosphoproteomic analysis identifies activation of the RET and IGF-1R/IR signaling pathways in neuroblastoma.

Neuroblastoma is an embryonal tumor of childhood with a heterogenous clinical presentation that reflects differences in activation of complex biological signaling pathways. Protein phosphorylation is a key component of cellular signal transduction and plays a critical role in processes that control...

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Autores principales: Bradley D DeNardo, Michael P Holloway, Qinqin Ji, Kevin T Nguyen, Yan Cheng, Marcus B Valentine, Arthur Salomon, Rachel A Altura
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/3f71b98240e84df3b04a1375baad4496
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