Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves?

Although there are abundant data highlighting the safety and efficacy of direct oral anticoagulants, to date, recent guidelines have limited their use to stroke prevention in patients with non-valvular AF, as well as in the prevention and treatment of venous thromboembolism and pulmonary embolism. E...

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Autores principales: Mahmoud Abdelnabi, Abdallah Almaghraby, Yehia Saleh
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Lenguaje:EN
Publicado: Radcliffe Medical Media 2020
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Acceso en línea:https://doaj.org/article/3f7a0c0fc0ee4d7b98debbb323263092
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spelling oai:doaj.org-article:3f7a0c0fc0ee4d7b98debbb3232630922021-12-04T16:02:29ZWill Direct Oral Anticoagulants Have a Chance in Prosthetic Valves?10.15420/ecr.2019.1.31758-37641758-3756https://doaj.org/article/3f7a0c0fc0ee4d7b98debbb3232630922020-02-01T00:00:00Zhttps://www.ecrjournal.com/articleindex/ecr.2019.1.3https://doaj.org/toc/1758-3756https://doaj.org/toc/1758-3764Although there are abundant data highlighting the safety and efficacy of direct oral anticoagulants, to date, recent guidelines have limited their use to stroke prevention in patients with non-valvular AF, as well as in the prevention and treatment of venous thromboembolism and pulmonary embolism. Encouraging data about the off-label use of direct oral anticoagulants have been shown in several other indications, such as intracardiac thrombi, left ventricular thrombi and left atrial appendage, but a large sector of patients are still not addressed, such as valvular and prosthetic patients.Mahmoud AbdelnabiAbdallah AlmaghrabyYehia SalehRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENEuropean Cardiology Review , Vol 15, Iss , Pp - (2020)
institution DOAJ
collection DOAJ
language EN
topic Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle Diseases of the circulatory (Cardiovascular) system
RC666-701
Mahmoud Abdelnabi
Abdallah Almaghraby
Yehia Saleh
Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves?
description Although there are abundant data highlighting the safety and efficacy of direct oral anticoagulants, to date, recent guidelines have limited their use to stroke prevention in patients with non-valvular AF, as well as in the prevention and treatment of venous thromboembolism and pulmonary embolism. Encouraging data about the off-label use of direct oral anticoagulants have been shown in several other indications, such as intracardiac thrombi, left ventricular thrombi and left atrial appendage, but a large sector of patients are still not addressed, such as valvular and prosthetic patients.
format article
author Mahmoud Abdelnabi
Abdallah Almaghraby
Yehia Saleh
author_facet Mahmoud Abdelnabi
Abdallah Almaghraby
Yehia Saleh
author_sort Mahmoud Abdelnabi
title Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves?
title_short Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves?
title_full Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves?
title_fullStr Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves?
title_full_unstemmed Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves?
title_sort will direct oral anticoagulants have a chance in prosthetic valves?
publisher Radcliffe Medical Media
publishDate 2020
url https://doaj.org/article/3f7a0c0fc0ee4d7b98debbb323263092
work_keys_str_mv AT mahmoudabdelnabi willdirectoralanticoagulantshaveachanceinprostheticvalves
AT abdallahalmaghraby willdirectoralanticoagulantshaveachanceinprostheticvalves
AT yehiasaleh willdirectoralanticoagulantshaveachanceinprostheticvalves
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