Closed-state inactivation and pore-blocker modulation mechanisms of human CaV2.2
Summary: N-type voltage-gated calcium (CaV) channels mediate Ca2+ influx at presynaptic terminals in response to action potentials and play vital roles in synaptogenesis, release of neurotransmitters, and nociceptive transmission. Here, we elucidate a cryo-electron microscopy (cryo-EM) structure of...
Saved in:
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Elsevier
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/3f815d9bfcb64a66b3a15ec8b32f971b |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|