Anthrax toxin translocation complex reveals insight into the lethal factor unfolding and refolding mechanism

Abstract Translocation is essential to the anthrax toxin mechanism. Protective antigen (PA), the binding component of this AB toxin, forms an oligomeric pore that translocates lethal factor (LF) or edema factor, the active components of the toxin, into the cell. Structural details of the translocati...

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Autores principales: Alexandra J. Machen, Mark T. Fisher, Bret D. Freudenthal
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3f8e058c49e347208faec432f78c2113
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