The Lumen of Human Intestinal Organoids Poses Greater Stress to Bacteria Compared to the Germ-Free Mouse Intestine: <named-content content-type="genus-species">Escherichia coli</named-content> Deficient in RpoS as a Colonization Probe

The Lumen of Human Intestinal Organoids Poses Greater Stress to Bacteria Compared to the Germ-Free Mouse Intestine: <named-content content-type="genus-species">Escherichia coli</named-content> Deficient in RpoS as a Colonization Probe

ABSTRACT Pluripotent stem-cell-derived human intestinal organoids (HIOs) are three-dimensional, multicellular structures that model a naive intestinal epithelium in an in vitro system. Several published reports have investigated the use of HIOs to study host-microbe interactions. We recently demonst...

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Autores principales: Madeline R. Barron, Roberto J. Cieza, David R. Hill, Sha Huang, Veda K. Yadagiri, Jason R. Spence, Vincent B. Young
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
RpoS
colonization
intestine
organoid
stress
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/3f9364e1354942f18694e094b73d3b36
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