Modeling regulatory network topology improves genome-wide analyses of complex human traits
Gene regulatory networks are a useful means of inferring functional interactions from large-scale genomic data. Here, the authors develop a Bayesian framework integrating GWAS summary statistics with gene regulatory networks to identify genetic enrichments and associations simultaneously.
Enregistré dans:
| Auteurs principaux: | , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/3f97afd99a364fa6b7fc3dfd5dfbd711 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|