Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions

Implantable biomaterials evoke foreign body responses in the central nervous system. The authors compare hydrogel-based biomaterials to identify cellular interactions and molecular mechanisms that drive different types of foreign body responses that have different effects on biomaterial function.

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Autores principales: Timothy M. OʼShea, Alexander L. Wollenberg, Jae H. Kim, Yan Ao, Timothy J. Deming, Michael V. Sofroniew
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/3f9ac0fa07be4aa38f0b487bb917087c
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spelling oai:doaj.org-article:3f9ac0fa07be4aa38f0b487bb917087c2021-12-02T15:34:36ZForeign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions10.1038/s41467-020-19906-32041-1723https://doaj.org/article/3f9ac0fa07be4aa38f0b487bb917087c2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19906-3https://doaj.org/toc/2041-1723Implantable biomaterials evoke foreign body responses in the central nervous system. The authors compare hydrogel-based biomaterials to identify cellular interactions and molecular mechanisms that drive different types of foreign body responses that have different effects on biomaterial function.Timothy M. OʼSheaAlexander L. WollenbergJae H. KimYan AoTimothy J. DemingMichael V. SofroniewNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Timothy M. OʼShea
Alexander L. Wollenberg
Jae H. Kim
Yan Ao
Timothy J. Deming
Michael V. Sofroniew
Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions
description Implantable biomaterials evoke foreign body responses in the central nervous system. The authors compare hydrogel-based biomaterials to identify cellular interactions and molecular mechanisms that drive different types of foreign body responses that have different effects on biomaterial function.
format article
author Timothy M. OʼShea
Alexander L. Wollenberg
Jae H. Kim
Yan Ao
Timothy J. Deming
Michael V. Sofroniew
author_facet Timothy M. OʼShea
Alexander L. Wollenberg
Jae H. Kim
Yan Ao
Timothy J. Deming
Michael V. Sofroniew
author_sort Timothy M. OʼShea
title Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions
title_short Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions
title_full Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions
title_fullStr Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions
title_full_unstemmed Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions
title_sort foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/3f9ac0fa07be4aa38f0b487bb917087c
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