Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions

Implantable biomaterials evoke foreign body responses in the central nervous system. The authors compare hydrogel-based biomaterials to identify cellular interactions and molecular mechanisms that drive different types of foreign body responses that have different effects on biomaterial function.

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Main Authors:	Timothy M. OʼShea, Alexander L. Wollenberg, Jae H. Kim, Yan Ao, Timothy J. Deming, Michael V. Sofroniew
Format:	article
Language:	EN
Published:	Nature Portfolio 2020
Subjects:	Science Q
Online Access:	https://doaj.org/article/3f9ac0fa07be4aa38f0b487bb917087c
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spelling	oai:doaj.org-article:3f9ac0fa07be4aa38f0b487bb917087c2021-12-02T15:34:36ZForeign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions10.1038/s41467-020-19906-32041-1723https://doaj.org/article/3f9ac0fa07be4aa38f0b487bb917087c2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19906-3https://doaj.org/toc/2041-1723Implantable biomaterials evoke foreign body responses in the central nervous system. The authors compare hydrogel-based biomaterials to identify cellular interactions and molecular mechanisms that drive different types of foreign body responses that have different effects on biomaterial function.Timothy M. OʼSheaAlexander L. WollenbergJae H. KimYan AoTimothy J. DemingMichael V. SofroniewNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Timothy M. OʼShea Alexander L. Wollenberg Jae H. Kim Yan Ao Timothy J. Deming Michael V. Sofroniew Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions
description	Implantable biomaterials evoke foreign body responses in the central nervous system. The authors compare hydrogel-based biomaterials to identify cellular interactions and molecular mechanisms that drive different types of foreign body responses that have different effects on biomaterial function.
format	article
author	Timothy M. OʼShea Alexander L. Wollenberg Jae H. Kim Yan Ao Timothy J. Deming Michael V. Sofroniew
author_facet	Timothy M. OʼShea Alexander L. Wollenberg Jae H. Kim Yan Ao Timothy J. Deming Michael V. Sofroniew
author_sort	Timothy M. OʼShea
title	Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions
title_short	Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions
title_full	Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions
title_fullStr	Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions
title_full_unstemmed	Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions
title_sort	foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/3f9ac0fa07be4aa38f0b487bb917087c
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Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions

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