A Translation-Aborting Small Open Reading Frame in the Intergenic Region Promotes Translation of a Mg <sup>2+</sup> Transporter in <i>Salmonella</i> Typhimurium
Translation initiation regions in mRNAs that include the ribosome-binding site (RBS) and the start codon are often sequestered within a secondary structure. Therefore, to initiate protein synthesis, the mRNA secondary structure must be unfolded to allow the RBS to be accessible to the ribosome.
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| Auteurs principaux: | , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2021
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| Accès en ligne: | https://doaj.org/article/3faa8c09d1b3491982297d5f67dec44a |
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| Résumé: | Translation initiation regions in mRNAs that include the ribosome-binding site (RBS) and the start codon are often sequestered within a secondary structure. Therefore, to initiate protein synthesis, the mRNA secondary structure must be unfolded to allow the RBS to be accessible to the ribosome. |
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