A Translation-Aborting Small Open Reading Frame in the Intergenic Region Promotes Translation of a Mg <sup>2+</sup> Transporter in <i>Salmonella</i> Typhimurium

Translation initiation regions in mRNAs that include the ribosome-binding site (RBS) and the start codon are often sequestered within a secondary structure. Therefore, to initiate protein synthesis, the mRNA secondary structure must be unfolded to allow the RBS to be accessible to the ribosome.

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Autores principales: Eunna Choi, Yoontak Han, Shinae Park, Hyojeong Koo, Jung-Shin Lee, Eun-Jin Lee
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/3faa8c09d1b3491982297d5f67dec44a
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Sumario:Translation initiation regions in mRNAs that include the ribosome-binding site (RBS) and the start codon are often sequestered within a secondary structure. Therefore, to initiate protein synthesis, the mRNA secondary structure must be unfolded to allow the RBS to be accessible to the ribosome.