A Translation-Aborting Small Open Reading Frame in the Intergenic Region Promotes Translation of a Mg <sup>2+</sup> Transporter in <i>Salmonella</i> Typhimurium

Translation initiation regions in mRNAs that include the ribosome-binding site (RBS) and the start codon are often sequestered within a secondary structure. Therefore, to initiate protein synthesis, the mRNA secondary structure must be unfolded to allow the RBS to be accessible to the ribosome.

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Autores principales: Eunna Choi, Yoontak Han, Shinae Park, Hyojeong Koo, Jung-Shin Lee, Eun-Jin Lee
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/3faa8c09d1b3491982297d5f67dec44a
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spelling oai:doaj.org-article:3faa8c09d1b3491982297d5f67dec44a2021-11-03T18:56:09Z A Translation-Aborting Small Open Reading Frame in the Intergenic Region Promotes Translation of a Mg <sup>2+</sup> Transporter in <i>Salmonella</i> Typhimurium 2150-751110.1128/mBio.03376-20https://doaj.org/article/3faa8c09d1b3491982297d5f67dec44a2021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03376-20https://doaj.org/toc/2150-7511 Translation initiation regions in mRNAs that include the ribosome-binding site (RBS) and the start codon are often sequestered within a secondary structure. Therefore, to initiate protein synthesis, the mRNA secondary structure must be unfolded to allow the RBS to be accessible to the ribosome.Eunna ChoiYoontak HanShinae ParkHyojeong KooJung-Shin LeeEun-Jin LeeAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Eunna Choi
Yoontak Han
Shinae Park
Hyojeong Koo
Jung-Shin Lee
Eun-Jin Lee
A Translation-Aborting Small Open Reading Frame in the Intergenic Region Promotes Translation of a Mg <sup>2+</sup> Transporter in <i>Salmonella</i> Typhimurium
description Translation initiation regions in mRNAs that include the ribosome-binding site (RBS) and the start codon are often sequestered within a secondary structure. Therefore, to initiate protein synthesis, the mRNA secondary structure must be unfolded to allow the RBS to be accessible to the ribosome.
format article
author Eunna Choi
Yoontak Han
Shinae Park
Hyojeong Koo
Jung-Shin Lee
Eun-Jin Lee
author_facet Eunna Choi
Yoontak Han
Shinae Park
Hyojeong Koo
Jung-Shin Lee
Eun-Jin Lee
author_sort Eunna Choi
title A Translation-Aborting Small Open Reading Frame in the Intergenic Region Promotes Translation of a Mg <sup>2+</sup> Transporter in <i>Salmonella</i> Typhimurium
title_short A Translation-Aborting Small Open Reading Frame in the Intergenic Region Promotes Translation of a Mg <sup>2+</sup> Transporter in <i>Salmonella</i> Typhimurium
title_full A Translation-Aborting Small Open Reading Frame in the Intergenic Region Promotes Translation of a Mg <sup>2+</sup> Transporter in <i>Salmonella</i> Typhimurium
title_fullStr A Translation-Aborting Small Open Reading Frame in the Intergenic Region Promotes Translation of a Mg <sup>2+</sup> Transporter in <i>Salmonella</i> Typhimurium
title_full_unstemmed A Translation-Aborting Small Open Reading Frame in the Intergenic Region Promotes Translation of a Mg <sup>2+</sup> Transporter in <i>Salmonella</i> Typhimurium
title_sort translation-aborting small open reading frame in the intergenic region promotes translation of a mg <sup>2+</sup> transporter in <i>salmonella</i> typhimurium
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/3faa8c09d1b3491982297d5f67dec44a
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