The in vivo genetic program of murine primordial lung epithelial progenitors

The identity of the earliest murine in vivo lung epithelial progenitors (marked by NKX2-1 expression) is unclear. Here, the authors use single-cell RNA sequencing to define the genetic program of these lung primordial progenitors, which will improve in vitro lung specification of pluripotent stem ce...

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Autores principales:	Laertis Ikonomou, Michael J. Herriges, Sara L. Lewandowski, Robert Marsland, Carlos Villacorta-Martin, Ignacio S. Caballero, David B. Frank, Reeti M. Sanghrajka, Keri Dame, Maciej M. Kańduła, Julia Hicks-Berthet, Matthew L. Lawton, Constantina Christodoulou, Attila J. Fabian, Eric Kolaczyk, Xaralabos Varelas, Edward E. Morrisey, John M. Shannon, Pankaj Mehta, Darrell N. Kotton
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3fb65185b9414530bfbace794788404c
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spelling	oai:doaj.org-article:3fb65185b9414530bfbace794788404c2021-12-02T14:40:30ZThe in vivo genetic program of murine primordial lung epithelial progenitors10.1038/s41467-020-14348-32041-1723https://doaj.org/article/3fb65185b9414530bfbace794788404c2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14348-3https://doaj.org/toc/2041-1723The identity of the earliest murine in vivo lung epithelial progenitors (marked by NKX2-1 expression) is unclear. Here, the authors use single-cell RNA sequencing to define the genetic program of these lung primordial progenitors, which will improve in vitro lung specification of pluripotent stem cells.Laertis IkonomouMichael J. HerrigesSara L. LewandowskiRobert MarslandCarlos Villacorta-MartinIgnacio S. CaballeroDavid B. FrankReeti M. SanghrajkaKeri DameMaciej M. KańdułaJulia Hicks-BerthetMatthew L. LawtonConstantina ChristodoulouAttila J. FabianEric KolaczykXaralabos VarelasEdward E. MorriseyJohn M. ShannonPankaj MehtaDarrell N. KottonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Laertis Ikonomou Michael J. Herriges Sara L. Lewandowski Robert Marsland Carlos Villacorta-Martin Ignacio S. Caballero David B. Frank Reeti M. Sanghrajka Keri Dame Maciej M. Kańduła Julia Hicks-Berthet Matthew L. Lawton Constantina Christodoulou Attila J. Fabian Eric Kolaczyk Xaralabos Varelas Edward E. Morrisey John M. Shannon Pankaj Mehta Darrell N. Kotton The in vivo genetic program of murine primordial lung epithelial progenitors
description	The identity of the earliest murine in vivo lung epithelial progenitors (marked by NKX2-1 expression) is unclear. Here, the authors use single-cell RNA sequencing to define the genetic program of these lung primordial progenitors, which will improve in vitro lung specification of pluripotent stem cells.
format	article
author	Laertis Ikonomou Michael J. Herriges Sara L. Lewandowski Robert Marsland Carlos Villacorta-Martin Ignacio S. Caballero David B. Frank Reeti M. Sanghrajka Keri Dame Maciej M. Kańduła Julia Hicks-Berthet Matthew L. Lawton Constantina Christodoulou Attila J. Fabian Eric Kolaczyk Xaralabos Varelas Edward E. Morrisey John M. Shannon Pankaj Mehta Darrell N. Kotton
author_facet	Laertis Ikonomou Michael J. Herriges Sara L. Lewandowski Robert Marsland Carlos Villacorta-Martin Ignacio S. Caballero David B. Frank Reeti M. Sanghrajka Keri Dame Maciej M. Kańduła Julia Hicks-Berthet Matthew L. Lawton Constantina Christodoulou Attila J. Fabian Eric Kolaczyk Xaralabos Varelas Edward E. Morrisey John M. Shannon Pankaj Mehta Darrell N. Kotton
author_sort	Laertis Ikonomou
title	The in vivo genetic program of murine primordial lung epithelial progenitors
title_short	The in vivo genetic program of murine primordial lung epithelial progenitors
title_full	The in vivo genetic program of murine primordial lung epithelial progenitors
title_fullStr	The in vivo genetic program of murine primordial lung epithelial progenitors
title_full_unstemmed	The in vivo genetic program of murine primordial lung epithelial progenitors
title_sort	in vivo genetic program of murine primordial lung epithelial progenitors
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/3fb65185b9414530bfbace794788404c
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The in vivo genetic program of murine primordial lung epithelial progenitors

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