Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8+ T cells

Long noncoding RNA (lncRNA) genes do not encode protein products yet are emerging as key regulators of cellular processes such as transcription and translation. Here, by examining lncRNA profiles from human and mouse CD8 T cells, the authors show that stages of CD8+ T cell differentiation are define...

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Autores principales: William H. Hudson, Nataliya Prokhnevska, Julia Gensheimer, Rama Akondy, Donald J. McGuire, Rafi Ahmed, Haydn T. Kissick
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/3fba6bfb088047b99a9728dd3fed18bd
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spelling oai:doaj.org-article:3fba6bfb088047b99a9728dd3fed18bd2021-12-02T16:51:01ZExpression of novel long noncoding RNAs defines virus-specific effector and memory CD8+ T cells10.1038/s41467-018-07956-72041-1723https://doaj.org/article/3fba6bfb088047b99a9728dd3fed18bd2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07956-7https://doaj.org/toc/2041-1723Long noncoding RNA (lncRNA) genes do not encode protein products yet are emerging as key regulators of cellular processes such as transcription and translation. Here, by examining lncRNA profiles from human and mouse CD8 T cells, the authors show that stages of CD8+ T cell differentiation are defined by expression of lncRNA genes.William H. HudsonNataliya ProkhnevskaJulia GensheimerRama AkondyDonald J. McGuireRafi AhmedHaydn T. KissickNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
William H. Hudson
Nataliya Prokhnevska
Julia Gensheimer
Rama Akondy
Donald J. McGuire
Rafi Ahmed
Haydn T. Kissick
Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8+ T cells
description Long noncoding RNA (lncRNA) genes do not encode protein products yet are emerging as key regulators of cellular processes such as transcription and translation. Here, by examining lncRNA profiles from human and mouse CD8 T cells, the authors show that stages of CD8+ T cell differentiation are defined by expression of lncRNA genes.
format article
author William H. Hudson
Nataliya Prokhnevska
Julia Gensheimer
Rama Akondy
Donald J. McGuire
Rafi Ahmed
Haydn T. Kissick
author_facet William H. Hudson
Nataliya Prokhnevska
Julia Gensheimer
Rama Akondy
Donald J. McGuire
Rafi Ahmed
Haydn T. Kissick
author_sort William H. Hudson
title Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8+ T cells
title_short Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8+ T cells
title_full Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8+ T cells
title_fullStr Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8+ T cells
title_full_unstemmed Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8+ T cells
title_sort expression of novel long noncoding rnas defines virus-specific effector and memory cd8+ t cells
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/3fba6bfb088047b99a9728dd3fed18bd
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