Hepatitis B virus X protein upregulates mTOR signaling through IKKβ to increase cell proliferation and VEGF production in hepatocellular carcinoma.

Hepatitis B virus X protein upregulates mTOR signaling through IKKβ to increase cell proliferation and VEGF production in hepatocellular carcinoma.

Hepatocellular carcinoma (HCC), a major cause of cancer-related death in Southeast Asia, is frequently associated with hepatitis B virus (HBV) infection. HBV X protein (HBx), encoded by a viral non-structural gene, is a multifunctional regulator in HBV-associated tumor development. We investigated n...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Chia-Jui Yen, Yih-Jyh Lin, Chia-Sheng Yen, Hung-Wen Tsai, Ting-Fen Tsai, Kwang-Yu Chang, Wei-Chien Huang, Pin-Wen Lin, Chi-Wu Chiang, Ting-Tsung Chang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/3fc1332225a941cc9c0cc6a080a2a129
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares