FREQUENCY OF HEPATOCELLULAR CARCINOMA AND ASSOCIATED SOCIODEMOGRAPHIC FACTORS IN TREATED PATIENTS OF CHRONIC HEPATITIS C

Objective: To look for frequency and associated socio-demographic factors of newly diagnosed patients of heap-tocellular carcinoma (HCC) among patients treated adequately for hepatitis C infection. Study Design: Correlational study. Place and Duration of Study: Gastroenterology Department, Pak Emira...

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Autores principales:	Rabia Tariq, Anum Abbas, Farrukh Saeed, Zafar Ali Qureshi
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2021
Materias:	heaptocellular carcinoma hepatitis c virus incidence treated Medicine R Medicine (General) R5-920
Acceso en línea:	https://doi.org/10.51253/pafmj.v71iSuppl-1.2602 https://doaj.org/article/3fcb4c609a5147fabc0c9daa0678d9f5
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spelling	oai:doaj.org-article:3fcb4c609a5147fabc0c9daa0678d9f52021-12-02T15:01:00ZFREQUENCY OF HEPATOCELLULAR CARCINOMA AND ASSOCIATED SOCIODEMOGRAPHIC FACTORS IN TREATED PATIENTS OF CHRONIC HEPATITIS Chttps://doi.org/10.51253/pafmj.v71iSuppl-1.26020030-96482411-8842https://doaj.org/article/3fcb4c609a5147fabc0c9daa0678d9f52021-01-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/2602https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To look for frequency and associated socio-demographic factors of newly diagnosed patients of heap-tocellular carcinoma (HCC) among patients treated adequately for hepatitis C infection. Study Design: Correlational study. Place and Duration of Study: Gastroenterology Department, Pak Emirates Military Hospital Rawalpindi, from Nov 2017 to Oct 2018. Methodology: This analysis was performed on 170 patients treated effectively for hepatitis C with standard anti-viral therapy at our hospital. They were followed up for two years after the sustained viral response has been achieved. Ultrasonography was done in all cases and contrast enhanced computerized tomography scan done on patients who were positive on ultrasound. Factors like age, gender, genotype of heaptocellular carcinoma, presence of cirrhosis and model for end-stage liver disease (MELD) score were related with presence of heaptocellular carcinoma among the target population. Results: Out of 170 patients included in final analysis 121 were male, 49 were female. About 53 patients were diagnosed as suffering from heaptocellular carcinoma while 117 were negative for that. Thirty six patients had cirrhosis while 134 non cirrhotic. After applying the binary logistic regression genotypes other than 3, high model for end-stage liver disease score & presence of cirrhosis had a strong relationship with presence of heaptocellular carcinoma among the patients treated for hepatitis C virus. Conclusion: Physicians and patients cannot ignore the possibility of a malignant outcome even after successful treatment of hepatitis C. Local protocols should be set for screening especially the high risk cases even after treatment of hepatitis C virus with special attention to patients with genotype other than 3, cirrhosis & high model for end-stage liver disease score on follow up visits.Rabia TariqAnum AbbasFarrukh SaeedZafar Ali QureshiArmy Medical College Rawalpindiarticleheaptocellular carcinomahepatitis c virusincidencetreatedMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss SUPPL-1, Pp 52-56 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	heaptocellular carcinoma hepatitis c virus incidence treated Medicine R Medicine (General) R5-920
spellingShingle	heaptocellular carcinoma hepatitis c virus incidence treated Medicine R Medicine (General) R5-920 Rabia Tariq Anum Abbas Farrukh Saeed Zafar Ali Qureshi FREQUENCY OF HEPATOCELLULAR CARCINOMA AND ASSOCIATED SOCIODEMOGRAPHIC FACTORS IN TREATED PATIENTS OF CHRONIC HEPATITIS C
description	Objective: To look for frequency and associated socio-demographic factors of newly diagnosed patients of heap-tocellular carcinoma (HCC) among patients treated adequately for hepatitis C infection. Study Design: Correlational study. Place and Duration of Study: Gastroenterology Department, Pak Emirates Military Hospital Rawalpindi, from Nov 2017 to Oct 2018. Methodology: This analysis was performed on 170 patients treated effectively for hepatitis C with standard anti-viral therapy at our hospital. They were followed up for two years after the sustained viral response has been achieved. Ultrasonography was done in all cases and contrast enhanced computerized tomography scan done on patients who were positive on ultrasound. Factors like age, gender, genotype of heaptocellular carcinoma, presence of cirrhosis and model for end-stage liver disease (MELD) score were related with presence of heaptocellular carcinoma among the target population. Results: Out of 170 patients included in final analysis 121 were male, 49 were female. About 53 patients were diagnosed as suffering from heaptocellular carcinoma while 117 were negative for that. Thirty six patients had cirrhosis while 134 non cirrhotic. After applying the binary logistic regression genotypes other than 3, high model for end-stage liver disease score & presence of cirrhosis had a strong relationship with presence of heaptocellular carcinoma among the patients treated for hepatitis C virus. Conclusion: Physicians and patients cannot ignore the possibility of a malignant outcome even after successful treatment of hepatitis C. Local protocols should be set for screening especially the high risk cases even after treatment of hepatitis C virus with special attention to patients with genotype other than 3, cirrhosis & high model for end-stage liver disease score on follow up visits.
format	article
author	Rabia Tariq Anum Abbas Farrukh Saeed Zafar Ali Qureshi
author_facet	Rabia Tariq Anum Abbas Farrukh Saeed Zafar Ali Qureshi
author_sort	Rabia Tariq
title	FREQUENCY OF HEPATOCELLULAR CARCINOMA AND ASSOCIATED SOCIODEMOGRAPHIC FACTORS IN TREATED PATIENTS OF CHRONIC HEPATITIS C
title_short	FREQUENCY OF HEPATOCELLULAR CARCINOMA AND ASSOCIATED SOCIODEMOGRAPHIC FACTORS IN TREATED PATIENTS OF CHRONIC HEPATITIS C
title_full	FREQUENCY OF HEPATOCELLULAR CARCINOMA AND ASSOCIATED SOCIODEMOGRAPHIC FACTORS IN TREATED PATIENTS OF CHRONIC HEPATITIS C
title_fullStr	FREQUENCY OF HEPATOCELLULAR CARCINOMA AND ASSOCIATED SOCIODEMOGRAPHIC FACTORS IN TREATED PATIENTS OF CHRONIC HEPATITIS C
title_full_unstemmed	FREQUENCY OF HEPATOCELLULAR CARCINOMA AND ASSOCIATED SOCIODEMOGRAPHIC FACTORS IN TREATED PATIENTS OF CHRONIC HEPATITIS C
title_sort	frequency of hepatocellular carcinoma and associated sociodemographic factors in treated patients of chronic hepatitis c
publisher	Army Medical College Rawalpindi
publishDate	2021
url	https://doi.org/10.51253/pafmj.v71iSuppl-1.2602 https://doaj.org/article/3fcb4c609a5147fabc0c9daa0678d9f5
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FREQUENCY OF HEPATOCELLULAR CARCINOMA AND ASSOCIATED SOCIODEMOGRAPHIC FACTORS IN TREATED PATIENTS OF CHRONIC HEPATITIS C

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